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2.A.1.3.59
MDR efflux pump, NorC (Truong-Bolduc et al. 2006). Proposed to be a quinolone resistance exporter, NorB (Marklevitz and Harris 2016). The 3-d x-ray structure at 3.6 Å resolution has been solved in an outward open configuration (Kumar et al. 2021). The structure shows that NorC specifically interacts with an organic cation, tetraphenylphosphonium.

Accession Number:D1GUL7
Protein Name:Putative transporter protein
Length:462
Molecular Weight:48937.00
Species:Staphylococcus aureus (strain TW20 / 0582) [663951]
Number of TMSs:14
Substrate Quinolones

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNETYRGGNK LILGIVLGVI TFWLFAQSLV NVVPNLQQSF GADMGTISIA VSLTALFSGM 
61:	FVVGAGGLAD KIGRVKMTNI GLLLSIIGSA LIIITNLPAL LILGRIIQGV SAACIMPSTL 
121:	AIMKTYYEGA ERQRALSYWS IGSWGGSGIC SLFGGAVATT MGWRWIFIFS IIVAVLSMLL 
181:	IKGTPETKSE VTNTHKFDVA GLIVLVVMLL SLNVVITKGA ALGYTSLWFF GLIAIVIVAF 
241:	FIFLNVEKKV DNPLIDFKLF ENKPYTGATI SNFLLNGVAG TLIVANTFVQ QGLGYTALQA 
301:	GYLSITYLIM VLLMIRVGEK LLQKMGSKRP MLLGTFIVII GIALISLVFL PGIFYVISCV 
361:	VGYLCFGLGL GIYATPSTDT AISNAPLDKV GVASGIYKMA SSLGGAFGVA ISGAVYAGAV 
421:	AATSIHTGAM IALWVNVLMG IMAFIAILFA IPNDDKRVKD AK