2.A.1.3.64
Uptake permease for cholate (steroid) metabolites, CamM of 513 aas and 14 TMSs. Uptake of 3,7(R),12(S)-trihydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oate was observed (Swain et al. 2012).
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| Accession Number: | Q0S4G7 |
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| Protein Name: | Multidrug transporter, MFS superfamily protein |
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| Length: | 513 |
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| Molecular Weight: | 53159.00 |
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| Species: | Rhodococcus sp. (strain RHA1) [101510] |
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| Number of TMSs: | 14 |
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| Substrate |
cholate |
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1: MVDVTGRHAR LGVLILSNPP EPHMHNMPLS PGEAERAPLS RGKAFALLAL IILLVEVIPL
61: AYNFVTPALP EIAKHFGTAN VGWVITIVTL MLAASTPLVG KLGDIYGKKR MMLVSAAVFG
121: VGSLLGALAP NFELFLVGRG LQGAGMAILV LAYGLIRDIL PPSIIPVAVG FVATGMGAST
181: ILGPIIGGYL IDHFGYTGVF WAQLLHVAVV GIAVAIFVPE TTLRTRSKLD VLGAAILGLG
241: AFVLLFGIGK ATAWGYTAPQ TLLCVGGGLA ILAGWLLYER TPKEPLIDLQ MLKHGPVAKT
301: LAASGFVQFV LVSHSMLIPM FVMTDPDLGL GYGFGVTALA VAIYTVPTGV VSMIAGPVGG
361: YFTRRIGPAP VLVFGGASLA LGSFLLATLH HSTVQMMFGQ LVIGLGLGSA SATLPNLIMR
421: TVPAQTQGIA GGMLNLSGSL GSAIGSQVMI AIVAIPGVVL VGRAAQYSEK GFVYAFFTLA
481: VAGMLAAVMG LLLIRNKIER PVDVASPKSE MVA