2.A.1.3.73
Multidrug resistance Mfs1 protein of 583 aas and 14 TMSs. Exports natural mycotoxins and a variety of fungicides in Mycosphaerella graminicola (Roohparvar et al. 2007). Etridiazole (EDZ) is a thiadiazole-containing fungicide commonly used to control Pythium and Phytophthora spp. Studies have shown that EDZ is teratogenic. A zebrafish (Danio rerio; ZF) model has been used to explore the molecular pathways associated with EDZ toxicity, and itwas concluded that there are several (Vasamsetti et al. 2023).
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| Accession Number: | A4ZGP3 |
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| Protein Name: | Major facilitator superfamily transporter |
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| Length: | 583 |
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| Molecular Weight: | 62476.00 |
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| Species: | Zymoseptoria tritici (Speckled leaf blotch fungus) [1047171] |
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| Number of TMSs: | 14 |
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| Substrate |
Cercosporin, fungicide, mycotoxin |
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1: MRFFSKKSPA AVVDSTAPSS SHHLDSDAEH YNEKPEPVED ITTPVRNSSE VNNPAEAKVE
61: AIENEALSRQ FSKDYPTGLK LTLITLALCL SVLCMALDNT IISTAIPRIT DQFNSIDDVG
121: WYGSSYLLTT CALQLFFGKL YTFYSIKTIY LTALVIFEIG SAVCGAAPNS IALIIGRAIA
181: GVGSAGIFSG AILIVANTVP LEKRPIYTGF IGGMYGIASV VGPLMGGAFT DHVSWRWCFY
241: INLPLGAITI AFIVFFYHPT KSAAQTIATT WRSKLQQFDI FGTLVFLPMI VCLLLALQWG
301: GSKYPWSDGK VIALFVVFGV LLLIFATIQV LKADHATVPP RLLRNRTVAG ACWFVLCLGG
361: AFFIFIYYLP LWFQAIKGAA PTKSGIMNIP LVLGLVLMSI LSGGLITVIG YYTPFVIASS
421: IFMAIGAGML STFTPATGSP KWIGFQVLFG IGVGLGMQQP LIAVQAVLPA KDVPIGTAMI
481: MFSQTLGGAL FIAVAQNVFS TQLLKNLRSI VPDLDPRIVL EAGATTLVKS VPGESLMGVR
541: LAYNDSIMSA FLVATAMATI SVLGAVAFEW KSVKGKKIEM GGA