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2.A.1.30.1
Putative abietane uptake permease (in a gene cluster for degradation of abietane diterpenoids), DitE, of 547 aas and 12 TMSs (Martin and Mohn 2000). Abietane diterpenoids are defense compounds synthesized by trees that are abundant in natural environments and occur as significant pollutants from pulp and paper production (Smith et al. 2007).

Accession Number:Q9X4X4
Protein Name:DitE
Length:547
Molecular Weight:58500.00
Species:Pseudomonas abietaniphila [89065]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate abietane

Cross database links:

Pfam: PF05977   

References (4)

[1] “Physiological and phylogenetic diversity of bacteria growing on resin acids.”  Mohn W.W.et.al.   10188280
[2] “A novel aromatic-ring-hydroxylating dioxygenase from the diterpenoid-degrading bacterium Pseudomonas abietaniphila BKME-9.”  Martin V.J.et.al.   10217753
[3] “Genetic investigation of the catabolic pathway for degradation of abietane diterpenoids by Pseudomonas abietaniphila BKME-9.”  Martin V.J.et.al.   10850995
[4] “A cytochrome P450 involved in the metabolism of abietane diterpenoids by Pseudomonas abietaniphila BKME-9.”  Smith D.J.et.al.   15150251

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDLSGLSPD EPAVPRAQPA SAWAPIRNRS FRWLWCGGAM VNLAIWMQTV GAAWIMTLLS 
61:	TSPLMVSLVQ TAISLPAFLF GLPGGVIADL VDRRKWLMMT QGVMLIAAAA LSVLSSLDML 
121:	SDWSLLAFTF LLGTGSALSM SAWMVTIVSV LPRDQVPAAI SLNGISTNAA RALGPALAGG 
181:	LIAYWNAASV FVIITVCLAL VIVLVAAFTP RQTPHALPAE NFAAGLRSGV RYIRHSAVLV 
241:	SALKQVFIFT LSASALWALL PLVAKHELGM DAGGYGLLMG FLGAGAVAGA LNLTAMYRRF 
301:	PLRVLIIAGT AGFALATLVA ALSHSRWAVC GTLMIAGMSW MAVNATISTV VQTCAANWVR 
361:	ARVASVYLLM LMGAMAIGGA IWGTLAEYLG LQNSLVLAAV TLGVGLILTR SGRLELGQEA 
421:	DYASAIQPTD RLLVPEQLNP GPGPVSIELA YRVAPEDRAN FIAVAYAVGQ SRRRNGAKNW 
481:	RLYHDLDEDG HYVERFIVES WLDYLRQQSR TTQADQLLEA RLSGMRCDAQ ISRRYIHQPL 
541:	AGAPENN