2.A.1.36.4
MdrA. Putative MDR transporter that may export cationic and hydrophobic compounds, Sco4007. Regulated by a TetR-like repressor that binds drugs (Hayashi et al. 2013).
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| Accession Number: | Q9ADP8 |
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| Protein Name: | Putative integral membrane protein |
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| Length: | 430 |
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| Molecular Weight: | 43013.00 |
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| Species: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [100226] |
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| Number of TMSs: | 12 |
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| Substrate |
drug |
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1: MPSSPSSTTP APTSTPAARR EPSGKGPSGA AARLFLPLIA LCTAVTAANI YLAAPLLPLI
61: AHDMGSTPSA VAWLASVAQL GYAAGLLFFA PLGDSVNRRR LVAALSLVAT AALLTAAASA
121: GTGALAGAVL VASAATVVPQ LLVPLVAERA PADRRARHVA AVIAGLFTGV VAARVLGGLA
181: GQAFGWRAVF VGAAVLTAVL GLATAYILPV ERRQRRGPLF AGLVAIPGLV RRSPDLWRAC
241: VRQAGMYGAW SALWTSLALL LTEGEGYGMT TAAAGLFGLF GLAASVVAPL AGGLVDRFGA
301: AKVVRSAYAL AALSVPLFWL GGQVMAALCA AAVLVHAALV ASHVANQTLA LTTTSAPATA
361: NTAYVVAGFA GGALASALAG PAFGHWGWGG VCAVAGAWLV LGWTATAVRP ARSARSARSA
421: RSVRSVRSAR