TCDB » SEARCH

« See all members of the family

2.A.1.4.7 Putative glycerol-3-phosphate (G-3-P) transporter, G3PP (most similar to TC# 2.A.1.4.6, 22% identity). Has been shown to catalyze glucose 6-P:P_i antiport across the endoplasmic reticular membrane(Pan et al. 2011).
Accession Number:	P57057
Protein Name:	Glycerol-3-phosphate transporter aka G3PP
Length:	533
Molecular Weight:	57662.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	phosphate(3-), sn-glycerol 3-phosphate, sn-glycerol 3-phosphate(2-), D-glucopyranose 6-phosphate

RefSeq:	NP_061837.3
Entrez Gene ID:	54020
Pfam:	PF07690
OMIM:	608094 gene
KEGG:	hsa:54020 hsa:54020
Gene Ontology GO:0016021 C:integral to membrane GO:0008643 P:carbohydrate transport GO:0055085 P:transmembrane transport GO:0005215 F:transporter activity
References (3) [1] “Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.” Bartoloni L.et.al. 11112347 [2] “Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.” Bartoloni L.et.al. 11112347 [3] “The DNA sequence of human chromosome 21.” Hattori M.et.al. 10830953

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MARLPAGIRF IISFSRDQWY RAFIFILTFL LYASFHLSRK PISIVKGELH KYCTAWDEAD 
61:	VRFSSQNRKS GSAAPHQLPD NETDCGWAPF DKNNYQQLLG ALDYSFLCAY AVGMYLSGII 
121:	GERLPIRYYL TFGMLASGAF TALFGLGYFY NIHSFGFYVV TQVINGLVQT TGWPSVVTCL 
181:	GNWFGKGRRG LIMGVWNSHT SVGNILGSLI AGYWVSTCWG LSFVVPGAIV AAMGIVCFLF 
241:	LIEHPNDVRC SSTLVTHSKG YENGTNRLRL QKQILKSEKN KPLDPEMQCL LLSDGKGSIH 
301:	PNHVVILPGD GGSGTAAISF TGALKIPGVI EFSLCLLFAK LVSYTFLFWL PLYITNVDHL 
361:	DAKKAGELST LFDVGGIFGG ILAGVISDRL EKRASTCGLM LLLAAPTLYI FSTISKMGLE 
421:	ATIAMLLLSG ALVSGPYTLI TTAVSADLGT HKSLKGNAHA LSTVTAIIDG TGSVGAALGP 
481:	LLAGLLSPSG WSNVFYMLMF ADACALLFLI RLIHKELSCP GSATGDQVPF KEQ

2.A.1.4.7
Putative glycerol-3-phosphate (G-3-P) transporter, G3PP (most similar to TC# 2.A.1.4.6, 22% identity). Has been shown to catalyze glucose 6-P:P_i antiport across the endoplasmic reticular membrane(Pan et al. 2011).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.1.4.7Putative glycerol-3-phosphate (G-3-P) transporter, G3PP (most similar to TC# 2.A.1.4.6, 22% identity). Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane(Pan et al. 2011).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.1.4.7
Putative glycerol-3-phosphate (G-3-P) transporter, G3PP (most similar to TC# 2.A.1.4.6, 22% identity). Has been shown to catalyze glucose 6-P:P_i antiport across the endoplasmic reticular membrane(Pan et al. 2011).