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2.A.1.46.2 Putative MDR efflux transporter of 390 aas and 12 TMSs. The closest homolologues are MDR pumps in subfamilies 2.A.1.2 and 2.A.1.3.
Accession Number:	Q83N16
Protein Name:	Putative transporter
Length:	390
Molecular Weight:	40609.00
Species:	Tropheryma whipplei [203267]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate

RefSeq:	NP_787325.1
Entrez Gene ID:	1482465
Pfam:	PF07690
BioCyc:	TWHI203267:TW197-MONOMER
KEGG:	twh:TWT197
Gene Ontology GO:0055085 P:transmembrane transport
References (1) [1] “Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome.” Raoult D.et.al. 12902375

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MVFIPSVLSS MVEGGLLPSV ALIAAHESSS SALAGLAVSA GLIGYLASNI PGGIVVSRFG 
61:	ELRGMMIALS CAGISVLINI FSSSVALLTF GVFLSGFSFG AYGVARHSFM TLYTPLKVRA 
121:	RAFSVLGGAF RLGGALGTFL VSGVVVLTGN VRSVFVVHLA IVILLVIFLF LVRNVQKTDK 
181:	SPKMLAEQPN SIKAMWEAVQ SKKGQLITIG SAAGILAAAR VSRSVILPLV GLHVGLKPEQ 
241:	ITFIIGIGST LEAFLFYSSG YVMDKWGRVW SAAPALFMVG GAYLLVFFAE SYVAFLAISL 
301:	LMGIGNALGS GIILTLGADL AGTSDQTAFI SVWRLVTDIG QSVGPLGMST LLGITSLTGA 
361:	AGVMGLTCFA AAGIMIRYLH IYLPNKRAKT

2.A.1.46.2
Putative MDR efflux transporter of 390 aas and 12 TMSs. The closest homolologues are MDR pumps in subfamilies 2.A.1.2 and 2.A.1.3.

Cross database links:

Gene Ontology

References (1)

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Analyze:

2.A.1.46.2Putative MDR efflux transporter of 390 aas and 12 TMSs. The closest homolologues are MDR pumps in subfamilies 2.A.1.2 and 2.A.1.3.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.46.2
Putative MDR efflux transporter of 390 aas and 12 TMSs. The closest homolologues are MDR pumps in subfamilies 2.A.1.2 and 2.A.1.3.