2.A.1.6.8 The acetate/monochloroacetate (haloacid) permease, Deh4p (Km = 5.5 mμM for acetate; 9 mμM for monochloroacetate) (Yu et al., 2007; Su and Tsang 2012).
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Accession Number: | Q7X4L6 |
Protein Name: | Deh4p |
Length: | 552 |
Molecular Weight: | 59415.00 |
Species: | Burkholderia cepacia GN=deh4p PE=4 SV=1 [292] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
Substrate |
acetate, chloroacetate |
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Pfam: |
PF00083
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[1] “Use of ribosomal promoters from Burkholderia cenocepacia and Burkholderia cepacia for improved expression of transporter protein in Escherichia coli.” Yu M. et.al. 16737826
[2] “Isolation and Characterization of a Novel Haloacid Permease from Burkholderia cepacia MBA4.” Yu M. et.al. 17545323
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1: MATIEGRAAP APITSEERRV IFASSLGTVF EWYDFYLAGS LAIYISRTFF SGVNPAAGFV
61: FTLLGFAAGF AVRPFGAIVF GRLGDMIGRK YTFLATILLM GLSTFVVGLL PGYGTIGMTA
121: PVVFIAMRML QGLALGGEYG GAATYVAEHA PSNKRGAWTA WIQTTATLGL FISLLVILSV
181: RSLLNEDTFA AWGWRVPFLV SIVLLAVSVW IRMQLHESPV FERIKAEGKT SKAPLSEAFG
241: QWKNLKIVLL ALFGLTAGQA VVWYTGQFYT LFFLTQTLKV DGTSANMLVA VALLIGTPFF
301: LFFGSLSDKI GRKPIIMAGC LIAALTYFPL FKALAHYTNP KLEAATLQAP ITMIADPSEC
361: SFQFNPVGTA KFTSSCDVAK GALSKAGLNY ENITAPAGTV AQIRIGDKVV DAYDGKAADA
421: KARGAEFEQT LSKSLETAGY PAKADPALIN WPMSILILTI LVLYVTMVYG PLAAMLVEMF
481: PARIRYTSMS LPYHIGNGWF GGFLPATAFA IIAARGNIYS GLWYPIVIAS VAFVIGTLFV
541: KETKGSSTYD AD