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2.A.1.65.10 Major facilitator superfamily domain-containing protein 6-like, MfsD6Ls, of 586 aas and 12 TMSs. Mutations can cause pediatric cataracts (Aldahmesh et al. 2012).
Accession Number:	Q8IWD5
Protein Name:	Major facilitator superfamily domain-containing protein 6-like
Length:	586
Molecular Weight:	64005.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	9
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate

Entrez Gene ID:	162387
KEGG:	hsa:162387
Gene Ontology GO:0016021 C:integral to membrane
References (3) [1] “Large-scale cDNA transfection screening for genes related to cancer development and progression.” Wan D.et.al. 15498874 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSANPRWDIS RALGVAKLFH LVCGVREACV TPFLTLYLRQ LGLAAPWVGT LMGTKHLIAA 
61:	FWAPVCAFLA KSYRKRRALL IGSLLGSVGA SLLMVLVPPV DKNRVHFPCN GSSGLTSTDA 
121:	LPGVTLPVNI TSAQESASSH PAKRTAEVEM PGFRNPPGES DRETFRDLHV YLAPSVEGAR 
181:	TTSQALLHPV TSGLKDHPWE VTFEVVKTAL PLLPGGKGPG NPANLSGTKG KAWAFDLSLE 
241:	ALRRTFILSL GSVAFWELLT APLEQVADDS LYEFLDFVDA TDRYRSLWVW RLLGMSAGVC 
301:	GITALVGQLD CFLMTSGPRG VVHFYGYSVV STLALLVSIA FPIPICQQWE PSYKRVKALS 
361:	IVGGDPHLIL LASTTVLVGA IVSTVQNFLF WHMKDHGSGE LVMGFSVALS LLGEILLHPF 
421:	KATLLRKLSR TGLVGLGLSC LAGQLLYYSF LWSWWSVLPI QILSAISNRA LWWAVGASVE 
481:	DLATPRMERA LSALFRGHFY GSGCSLGSFV GGFVVMRFSL AVLYQACCVA LLLWLALLLS 
541:	IQRRLPRERK IKYSKLLSME VSDTSDSEQG TEQDWLVKAM REEHSD

2.A.1.65.10
Major facilitator superfamily domain-containing protein 6-like, MfsD6Ls, of 586 aas and 12 TMSs. Mutations can cause pediatric cataracts (Aldahmesh et al. 2012).

Cross database links:

Gene Ontology

References (3)

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2.A.1.65.10Major facilitator superfamily domain-containing protein 6-like, MfsD6Ls, of 586 aas and 12 TMSs. Mutations can cause pediatric cataracts (Aldahmesh et al. 2012).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.1.65.10
Major facilitator superfamily domain-containing protein 6-like, MfsD6Ls, of 586 aas and 12 TMSs. Mutations can cause pediatric cataracts (Aldahmesh et al. 2012).