2.A.1.66.1 MFS permease of unknown function (First half resembles 2.A.1.3.7 (e-11) and 2.A.1.15.3 (e-8)). Very likely to be a galactoside/galactose transporter; encoded within a gene cluster with β-galactosidase and galactose metabolic genes.
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Accession Number: | A1RW34 |
Protein Name: | Major facilitator superfamily MFS_1 |
Length: | 428 |
Molecular Weight: | 46528.00 |
Species: | Thermofilum pendens (strain Hrk 5) [368408] |
Number of TMSs: | 12 |
Substrate |
galactose, galactoside |
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Entrez Gene ID: |
4601889
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Pfam: |
PF07690
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KEGG: |
tpe:Tpen_0004
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[1] “Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction.” Anderson I. et.al. 18263724
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1: MPEGRPRVKV IVASLALFVL FYFMGYYMLN PILRTLHAEG LIPGKSEVEW RFNAGLIATL
61: LQGTGLVLSF VWGVLADKVG RRPVIFTLGV IMGLGLLLVS QARSYAELLA YFIAFGVGYV
121: GVGPAIYAFI SDALPSESRG RGYASYYVSS VLAMILGLIV AGVLLPWRTA YMLAGLLTLV
181: FSVLLFYSSR GIFIGYSEKG AREARRYSLR ESLPSLRKKS VLLVLLMIIP WTIPWGMLSI
241: WSIDYISTKW GVSTGTASLI IAAATASIAL GHIVGGTLSD RLAGKGDYTG RTKVSLLGVV
301: VGYVSMMLMV TYPYPYGSTN FKDLLVPSAL AVGGMMFTTF AYPNINTVLS EVVVPEHRGT
361: VFAVYSVLNN LGWTLGPTVY TLLLKAFSGV YADQVSAMTA AASTIVSLWL IPALCWLLLH
421: RVYPKEKI