TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.103.1.1









Cell division protein, FtsW.  May flip lipid II (involved in cell wall synthesis) across the cytoplasmic membrane.  R145 and K153 in TMS 4 (of 10) are esesential for this transport activity (Mohammadi et al. 2014).  There is some controversy about this transport function (Young 2014; Sham et al. 2014).  See TC#2.A.66.4.3 for the alternative explanation.

Bacteria
Pseudomonadota
FtsW of E. coli (P0ABG4)
2.A.103.1.2









Rod shape determining protein, RodA.  A proposed flippase for a lipid-linked disaccharide-pentapeptide cell wall precursor, but this proposal is controversial (Sham et al. 2014; Young 2014).

Bacteria
Pseudomonadota
RodA of E. coli (P0ABG7)
2.A.103.1.3









Sporulation protein, SpoVE.

Bacteria
Bacillota
SpoVE of Bacillus subtilis (P07373)
2.A.103.1.4









FtsW of 524 aas

Bacteria
Actinomycetota
FtsW of Mycobacterium tuberculosis
2.A.103.1.5









FtsW of 361 aas

Bacteria
Aquificota
FtsW of Hydrogenobacter thermophilus
2.A.103.1.6









FtsW of 385 aas

Bacteria
Thermotogota
FtsW of Marinitoga piezophila
2.A.103.1.7









FtsW of 448 aas and 123 TMSs

Bacteria
Actinomycetota
FtsW of Tropheryma whipplei (strain Twist) (Whipple's bacillus)
2.A.103.1.8









Bacteria
Chlamydiota
MrdB of Chlamydophila psittaci (Chlamydia psittaci)
2.A.103.1.9









Lipid flippase involved in cell envelope biogenesis, FtsW, of 456 aas and 10 TMSs (Bush et al. 2015).

Bacteria
Actinomycetota
FtsW of Streptomyces coelicolor
2.A.103.1.10









Rod shape-determining protein Rod, of 424 aas and 10 TMSs.

Bacteria
Bacteroidota
RodA of Lacinutrix venerupis
2.A.103.1.11









Uncharacterized protein of 423 aas and 10 TMSs

Bacteria
Bacillota
UP of Bacillus marisflavi
2.A.103.1.12









FtsW/RodA/SpoVE family cell cycle protein of 439 aas and 10 TM

Bacteria
Bacillota
FtsW of Anaerobacillus alkalidiazotrophicus