| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
2.A.103.1.1 | Cell division protein, FtsW. May flip lipid II (involved in cell wall synthesis) across the cytoplasmic membrane. R145 and K153 in TMS 4 (of 10) are esesential for this transport activity (Mohammadi et al. 2014). There is some controversy about this transport function (Young 2014; Sham et al. 2014). See TC#2.A.66.4.3 for the alternative explanation. | Bacteria |
Proteobacteria | FtsW of E. coli (P0ABG4) |
|
2.A.103.1.2 | Rod shape determining protein, RodA. A proposed flippase for a lipid-linked disaccharide-pentapeptide cell wall precursor, but this proposal is controversial (Sham et al. 2014; Young 2014). | Bacteria |
Proteobacteria | RodA of E. coli (P0ABG7) |
|
2.A.103.1.3 | Bacteria |
Firmicutes | SpoVE of Bacillus subtilis (P07373) | |
|
2.A.103.1.4 | FtsW of 524 aas | Bacteria |
Actinobacteria | FtsW of Mycobacterium tuberculosis |
|
2.A.103.1.5 | FtsW of 361 aas | Bacteria |
Aquificae | FtsW of Hydrogenobacter thermophilus |
|
2.A.103.1.6 | FtsW of 385 aas | Bacteria |
Thermotogae | FtsW of Marinitoga piezophila |
|
2.A.103.1.7 | FtsW of 448 aas and 123 TMSs | Bacteria |
Actinobacteria | FtsW of Tropheryma whipplei (strain Twist) (Whipple's bacillus) |
|
2.A.103.1.8 | Cell shape-determining protein, MrdB, of 379 aas | Bacteria |
Chlamydiae/Verrucomicrobia group | MrdB of Chlamydophila psittaci (Chlamydia psittaci) |
|
2.A.103.1.9 | Lipid flippase involved in cell envelope biogenesis, FtsW, of 456 aas and 10 TMSs (Bush et al. 2015). | Bacteria |
Actinobacteria | FtsW of Streptomyces coelicolor |
|
2.A.103.1.10 | Rod shape-determining protein Rod, of 424 aas and 10 TMSs. | Bacteria |
Bacteroidetes | RodA of Lacinutrix venerupis |
|
2.A.103.1.11 | Uncharacterized protein of 423 aas and 10 TMSs | Bacteria |
Firmicutes | UP of Bacillus marisflavi |
|
2.A.103.1.12 | FtsW/RodA/SpoVE family cell cycle protein of 439 aas and 10 TM | Bacteria |
Firmicutes | FtsW of Anaerobacillus alkalidiazotrophicus |