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2.A.106.1.5
Chloroplast thylakoid GDT-1-like protein or photosynthesis-affected protein-71, PAM71 or CCHA1 of 370 aas with 6 TMSs in a 3 + 3 TMS arrangement. It takes up Mn2+ and influences both Mn2+ and Ca2+ homeostasis in the chloroplast.  It is necessary for photosystem II function due to its Mn2+ uptake activity (Schneider et al. 2016; Hoecker et al. 2017).  It is an Mn2+/H+ exchanger, which transport Mn2+ from the chloroplast stroma into the acidic thylakoid lumen (Schneider et al. 2016).  It might be a chloroplast-localized Ca2+/H+ antiporter as well (Wang et al. 2016) since it regulates Ca2+, Mn2+ and pH homeostasis and is required for chloroplast development.

Accession Number:Q94AX5
Protein Name:GDT1-like protein 1, chloroplastic
Length:370
Molecular Weight:39074.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate calcium(2+), hydron, manganese(2+)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLSLNLSESL RIPFQNPRPP KSDFSSTSSS PSSSSRRCVS AYPIPIGFSV RNQYFSRCLT 
61:	QLRRNESQQL GFRCFQRNDA ACYLEKAESE EHDRNLDVLV ESSIAHSRRE IQRVLMFLAV 
121:	SGSVALLGTD PAFAASSIPN VTQSLVTSFG DLGDISSGFA SAFLLIFFSE LGDKTFFIAA 
181:	LLAARNSAAT VFVGTFGALG IMTIISVVLG RTFHYVDEVL PFRFGGTDLP IDDIAAVCLL 
241:	VYFGVSTLLD AVSDEGKADE EQKEAELAVS ELSGNGAGIV AAANTIISTF ALVFVAEWGD 
301:	KSFFSTIALA AASSPLGVIA GALAGHGAAT LLAVLGGSLL GNFLSEKAIA YVGGVLFLVF 
361:	AAVTVAEIVT