2.A.109.2.3
8 TMS membrane protein including a transmembrane domain homologous to other proteins in the TerC family (2.A.109) with the transmembrane domain having a 4 + 4 TMS arrangement, and a C-terminal domain (residues 622 - 889) with high sequence identity with hemolysin C and all members of the HlyC family (TC# 1.C.126), including some Mg2+ exporters in Cyclin M Mg2+ Exporter (CNNM) (TC family 1.A.112). The hydrophilic N-terminal CBS domain is an integrase domain but may bind ATP (Huang et al. 2021).
|
| Accession Number: | L5DDD7 |
|---|
| Protein Name: | Membrane protein |
|---|
| Length: | 896 |
|---|
| Molecular Weight: | 102582.00 |
|---|
| Species: | Escherichia coli KTE166 [1169397] |
|---|
| Number of TMSs: | 7 |
|---|
| Substrate |
|
|---|
1: MQMQHLMVGY PKYYQTADYA LRLSVMADIA TMRMKALHFW DKHDISAASE AFGVSCRTPY
61: WWRQLLNKGG PEGPIPHSKA PLVRRKKHWH PDVLKEIRRL RTELPNLGKE QIFVRLKPWC
121: VQRHLTCPSV STIGRMIATA HDKMRMIPVR LSSRGKALFV KKRTTKPRRP KHYRPVKTGE
181: LIGMDAIELR MGEMRRYIIT MIDEHSDYAL ALAVPSLNSD IVNHFFSRAA RLFPIGISQI
241: ISDNGKEFLG SFDKTLQEAA IKHIWTYPYT PKMNAICDRF NRTLREQFIE FNEILLFEDL
301: ALFNQKLAEY LVLYNSKRPH KALALMTPVE YMLKENKNCN MWWTHTLHFR LILSMIVITH
361: TAVVQVLIHM EWIADPSIWA GLVTLVVIEL VLGIDNLVFI AILAEKLPPA QRDRARITGL
421: MLAMVMRLLL LASISWLVTL TQPLFSFRSF TFSARDLIML FGGFFLLFKA TMELNERLEG
481: KDSNNPTQRK GAKFWGVVTQ IVVLDAIFSL DSVITAIGMV DHLLVMMAAV VIAISLMLMA
541: SKPLTQFVNS HPTIVILCLS FLLMIGFSLV AEGFGFVIPK GYLYAAIGFS VMIEAFNQLA
601: IFNRRRFLSA NQTLRQRTTE AVMRLLSGQK EDAELDTETA SMLVDHGNQQ IFNPQERRMI
661: ERVLNLNQRT VSSIMTSRHD IEHIDLNAPE DEIRQLLERN QHTRLVVTDG DDAEDLLGVV
721: HVIDLLQQSL RGEPLNLRVL IRQPLVFPET LPLLPALEQF RNARTHFAFV VDEFGSVEGI
781: VTLSDVTETI AGNLPNEVEE IDARHDIQKN ADGSWTANGH MPLEDLVQYV PLPLDEKREY
841: HTIAGLLMEY LQRIPKPGEE VQVGDYLLKT LQVESHRVQK VQIIPLRKDG EMEYEV