TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
2.A.120.1.1 | Putative permease of 349 aas | Bacteria |
Bacillota | PP of Staphylococcus epidermidis |
2.A.120.1.2 | Putative permease of 372 aas | Bacteria |
Bacillota | PP of Coprococcus catus |
2.A.120.1.3 | Putative permease of 496 aas | Bacteria |
Bacillota | PP of Clostridium botulinum |
2.A.120.1.4 | Putative permease of 378 aas | Bacteria |
Pseudomonadota | PP of Sphingopyxis alaskensis |
2.A.120.1.5 | Putative permease of 378 aas | Archaea |
Euryarchaeota | PP of Pyrococcus horikoshii |
2.A.120.1.6 | Putative permease of 326 aas | Bacteria |
Bacillota | PP of Caldicellulosiruptor kristjanssonii |
2.A.120.1.7 | Putative permease of 358 aas | Bacteria |
Bacillota | PP of Desulfotomaculum acetoxidans |
2.A.120.1.8 | Putative permease of 355 aas, ProT. It is 71% identical to the S. aureus ortholog, ProT (TC# 2.A.120.1.14), which has been shown to be the major proliine uptake transporter in S. aureus and is essential for infections in skin and soft tissues when external proline is provided as a source of this amino acid in minimal growth media (Lehman et al. 2023). | Bacteria |
Bacillota | ProT of Staphylococcus carnosus |
2.A.120.1.9 | Putative amino acid transporter, YyaD, which possibly plays a role in sporulation. | Bacteria |
Bacillota | YyaD of Bacillus subtilis |
2.A.120.1.10 | Putative amino acid transporter, YkvI | Bacteria |
Bacillota | YkvI of Bacillus subtilis |
2.A.120.1.11 | Putative amino acid uptake porter of 700 aas, BrkK, with a C-terminal Lactamase B domain. | Bacteria |
Bacillota | BrkK of Eubacterium brachy |
2.A.120.1.12 | Putative alanine:sodium symporter | Bacteria |
Bacillota | Putative transporter of Mogibacterium sp. |
2.A.120.1.13 | Uncharacterized protein | Archaea |
Thermoproteota | UP of Caldivirga maquilingensis |
2.A.120.1.14 | Proline transporter, ProT, of 355 aas and 10 TMSs in a 2 + 3 + 2 + 3 TMS arrangement. It is a major proline uptake transporter in S. aureus and is required for infection in skin and soft tissues. In minimal medium it is the major proline uptake porter (Lehman et al. 2023). Its ortholog in S. carnosis (TC# 2.A.120.1.8) is 71% identical to this protein. | Bacteria |
Bacillota | ProT of Staphylococcus aureus |