2.A.120.1.8 Putative permease of 355 aas, ProT. It is 71% identical to the S. aureus ortholog, ProT (TC# 2.A.120.1.14), which has been shown to be the major proliine uptake transporter in S. aureus and is essential for infections in skin and soft tissues when external proline is provided as a source of this amino acid in minimal growth media (Lehman et al. 2023).
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Accession Number: | B9DKA7 |
Protein Name: | Putative membrane protein |
Length: | 355 |
Molecular Weight: | 38454.00 |
Species: | Staphylococcus carnosus (strain TM300) [396513] |
Number of TMSs: | 10 |
Substrate |
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1: MTFNKETVKI GFAYVGVVVG AGFSTGQEVM QFFTDYGLYA YIGVLIAGLI LGFIGRQVAK
61: IGTAFDAENH ESTLSYLFGK QFGRIIDYIL VFFLFGISVT MIAGAGSAFH ESYGIPTWLG
121: SLIMVIAIYI TLLMDFNKIV RALGVVTPFL IVLVIVIAGV YLVKGQVPIS QINSVVPDAN
181: PIQGIWRGTI YGGLAFAVGF STIVAIGGDA SRRKVSGAGA LFGGVVYTIL LALITFALQT
241: EYPAIKDAAI PTLTLAHGIH PIVTILLSIV MLAVMYNTIL GLLYSFAARF TTPYTKKYHI
301: LIVIMMLVAY GLSFVGFSSL INFLYPAMGY VGLLIVIAVL IKYFKRKKEN KEHIA