2.A.124.1.1
The lysine exporter, LysO of 299 aas and 9 putative TMSs (Pathania and Sardesai 2015). Also exports the toxic lysine antimetabolite, thialysine. Topological analyses of LysO revealed a critical role for a conserved pair of intramembrane solvent-exposed acidic residues (Dubey et al. 2021).
|
| Accession Number: | P75826 |
|---|
| Protein Name: | Uncharacterized protein YbjE |
|---|
| Length: | 299 |
|---|
| Molecular Weight: | 32340.00 |
|---|
| Species: | Escherichia coli (strain K12) [83333] |
|---|
| Number of TMSs: | 9 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
1: MFSGLLIILV PLIVGYLIPL RQQAALKVIN QLLSWMVYLI LFFMGISLAF LDNLASNLLA
61: ILHYSAVSIT VILLCNIAAL MWLERGLPWR NHHQQEKLPS RIAMALESLK LCGVVVIGFA
121: IGLSGLAFLQ HATEASEYTL ILLLFLVGIQ LRNNGMTLKQ IVLNRRGMIV AVVVVVSSLI
181: GGLINAFILD LPINTALAMA SGFGWYSLSG ILLTESFGPV IGSAAFFNDL ARELIAIMLI
241: PGLIRRSRST ALGLCGATSM DFTLPVLQRT GGLDMVPAAI VHGFILSLLV PILIAFFSA