2.A.126.1.18
Transmembrane Protein 14C (TMEM14C) of 112 aas and 4 TMSs. It is a mitochondrial porphyrin (protoporphyrinogen) transporter, essential for haem biosynthesis. It is an SF3B1 splicing target (Steensma et al. 2021).
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| Accession Number: | Q9P0S9 |
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| Protein Name: | Transmembrane protein 14C |
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| Length: | 112 |
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| Molecular Weight: | 11565.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion membrane1 / Multi-pass membrane protein2 |
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| Substrate |
porphyrin |
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1: MQDTGSVVPL HWFGFGYAAL VASGGIIGYV KAGSVPSLAA GLLFGSLAGL GAYQLSQDPR
61: NVWVFLATSG TLAGIMGMRF YHSGKFMPAG LIAGASLLMV AKVGVSMFNR PH