2.A.126.1.19
TMEM14A of 99 aas and 4 TMSs. It inhibits apoptosis via negative regulation of the mitochondrial outer
membrane permeabilization involved in the apoptotic signaling pathway (). It inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of the mitochondrial membrane potential (Woo et al. 2011).
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| Accession Number: | Q9Y6G1 |
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| Protein Name: | Transmembrane protein 14A |
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| Length: | 99 |
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| Molecular Weight: | 10712.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MDLIGFGYAA LVTFGSIFGY KRRGGVPSLI AGLFVGCLAG YGAYRVSNDK RDVKVSLFTA
61: FFLATIMGVR FKRSKKIMPA GLVAGLSLMM ILRLVLLLL