2.A.126.1.20
TMEM14B of 114 aas and 4 TMSs. It is a primate-specific protein involved in cortical expansion and folding in
the developing neocortex. It may drive neural progenitor proliferation
through nuclear translocation of IQGAP1, which in turn promotes G1/S
cell cycle transitions (Liu et al. 2017).
|
| Accession Number: | Q9NUH8 |
|---|
| Protein Name: | Transmembrane protein 14B |
|---|
| Length: | 114 |
|---|
| Molecular Weight: | 12078.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Number of TMSs: | 4 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
1: MEKPLFPLVP LHWFGFGYTA LVVSGGIVGY VKTGSVPSLA AGLLFGSLAG LGAYQLYQDP
61: RNVWGFLAAT SVTFVGVMGM RSYYYGKFMP VGLIAGASLL MAAKVGVRML MTSD