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|---|---|
| Accession Number: | Q46839 |
| Protein Name: | YghK aka GLCA aka B2975 |
| Length: | 560 |
| Molecular Weight: | 58920.00 |
| Species: | Escherichia coli [83333] |
| Number of TMSs: | 18 |
| Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
| Substrate | lactate, glycolate |
Cross database links:
| DIP: | DIP-12206N |
|---|---|
| RefSeq: | AP_003529.1 NP_417449.1 |
| Entrez Gene ID: | 947259 |
| Pfam: | PF02652 |
| BioCyc: | EcoCyc:B2975-MONOMER ECOL168927:B2975-MONOMER |
| KEGG: | ecj:JW2942 eco:b2975 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015129
F:lactate transmembrane transporter activity
GO:0015727
P:lactate transport
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References (5)[1] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [3] “The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease.” Nunez M.F.et.al. 11283302 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MVTWTQMYMP MGGLGLSALV ALIPIIFFFV ALAVLRLKGH VAGAITLILS ILIAIFAFKM 61: PIDMAFAAAG YGFIYGLWPI AWIIVAAVFL YKLTVASGQF DIIRSSVISI TDDQRLQVLL 121: IGFSFGALLE GAAGFGAPVA ITGALLVGLG FKPLYAAGLC LIANTAPVAF GALGVPILVA 181: GQVTGIDPFH IGAMAGRQLP FLSVLVPFWL VAMMDGWKGV KETWPAALVA GGSFAVTQFF 241: TSNYIGPELP DITSALVSIV SLALFLKVWR PKNTETAISM GQSAGAMVVN KPSSGGPVPS 301: EYSLGQIIRA WSPFLILTVL VTIWTMKPFK ALFAPGGAFY SLVINFQIPH LHQQVLKAAP 361: IVAQPTPMDA VFKFDPLSAG GTAIFIAAII SIFILGVGIK KGIGVFAETL ISLKWPILSI 421: GMVLAFAFVT NYSGMSTTLA LVLAGTGVMF PFFSPFLGWL GVFLTGSDTS SNALFGSLQS 481: TTAQQINVSD TLLVAANTSG GVTGKMISPQ SIAVACAATG MVGRESELFR YTVKHSLIFA 541: SVIGIITLLQ AYVFTGMLVS