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2.A.17.2.2 Peptide:H⁺ symporter (dipeptides and tripeptides preferred (Cai et al., 2007). Substrate preference is altered by mutations in the fifth TMS of Ptr2p (Hauser et al. 2013).
Accession Number:	P32901
Protein Name:	PTR2 aka YKR093W aka YKR413
Length:	601
Molecular Weight:	68044.00
Species:	Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hydron, peptide

DIP:	DIP-5311N
RefSeq:	NP_013019.1
Entrez Gene ID:	853968
Pfam:	PF00854
KEGG:	sce:YKR093W
Gene Ontology GO:0016021 C:integral to membrane GO:0005624 C:membrane fraction GO:0005886 C:plasma membrane GO:0042936 F:dipeptide transporter activity GO:0042937 F:tripeptide transporter activity GO:0042938 P:dipeptide transport GO:0015031 P:protein transport GO:0042939 P:tripeptide transport
References (7) [1] “Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene.” Perry J.R.et.al. 8264579 [2] “The complete sequence of a 15,820 bp segment of Saccharomyces cerevisiae chromosome XI contains the UBI2 and MPL1 genes and three new open reading frames.” Bou G.et.al. 8154186 [3] “Complete DNA sequence of yeast chromosome XI.” Dujon B.et.al. 8196765 [4] “Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae.” Ficarro S.B.et.al. 11875433 [5] “A global topology map of the Saccharomyces cerevisiae membrane proteome.” Kim H.et.al. 16847258 [6] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.” Li X.et.al. 17330950 [7] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.” Albuquerque C.P.et.al. 18407956

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLNHPSQGSD DAQDEKQGDF PVIEEEKTQA VTLKDSYVSD DVANSTERYN LSPSPEDEDF 
61:	EGPTEEEMQT LRHVGGKIPM RCWLIAIVEL SERFSYYGLS APFQNYMEYG PNDSPKGVLS 
121:	LNSQGATGLS YFFQFWCYVT PVFGGYVADT FWGKYNTICC GTAIYIAGIF ILFITSIPSV 
181:	GNRDSAIGGF IAAIILIGIA TGMIKANLSV LIADQLPKRK PSIKVLKSGE RVIVDSNITL 
241:	QNVFMFFYFM INVGSLSLMA TTELEYHKGF WAAYLLPFCF FWIAVVTLIF GKKQYIQRPI 
301:	GDKVIAKSFK VCWILTKNKF DFNAAKPSVH PEKNYPWNDK FVDEIKRALA ACKVFIFYPI 
361:	YWTQYGTMIS SFITQASMME LHGIPNDFLQ AFDSIALIIF IPIFEKFVYP FIRRYTPLKP 
421:	ITKIFFGFMF GSFAMTWAAV LQSFVYKAGP WYNEPLGHNT PNHVHVCWQI PAYVLISFSE 
481:	IFASITGLEY AYSKAPASMK SFIMSIFLLT NAFGSAIGCA LSPVTVDPKF TWLFTGLAVA 
541:	CFISGCLFWL CFRKYNDTEE EMNAMDYEEE DEFDLNPISA PKANDIEILE PMESLRSTTK 
601:	Y

2.A.17.2.2
Peptide:H⁺ symporter (dipeptides and tripeptides preferred (Cai et al., 2007). Substrate preference is altered by mutations in the fifth TMS of Ptr2p (Hauser et al. 2013).

Cross database links:

Gene Ontology

References (7)

External Searches:

Analyze:

2.A.17.2.2Peptide:H+ symporter (dipeptides and tripeptides preferred (Cai et al., 2007). Substrate preference is altered by mutations in the fifth TMS of Ptr2p (Hauser et al. 2013).

Cross database links:

Gene Ontology

References (7)

External Searches:

Analyze:

2.A.17.2.2
Peptide:H⁺ symporter (dipeptides and tripeptides preferred (Cai et al., 2007). Substrate preference is altered by mutations in the fifth TMS of Ptr2p (Hauser et al. 2013).