2.A.17.3.25
Protein NRT1/ PTR FAMILY 5.8, NPF5.8 or NAEZT1, of 552 aas and 11 or 12 TMSs. NAET1 and NAET2, function as nicotianamide (nicotinamide NA) transporters required for translocation of both iron and copper to seeds. Chao et al. 2021 showed that NAET1 and NAET2 are predominantly expressed in the shoot and root vascular tissues and mediate secretion of NA out of the cells, resembling the release of neurotransmitters from animal synaptic vesicles (Chao et al. 2021).
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| Accession Number: | Q9LFR1 |
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| Protein Name: | Protein NRT1/ PTR FAMILY 5.8 |
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| Length: | 552 |
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| Molecular Weight: | 61732.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
nicotinamide |
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1: MAGGEKRRGL SKSCALLIVI AGIERYAFKG VASNLVTYLT DVVKMSNSRA ATTVNTWSGF
61: TFMLPLFSAP FADSYWDRFF TILASSSLYF VGLVGLTFTA FAGSRSTTKT ISLYFLYTSL
121: SLVALGLGVL NPSLQAFGAD QLDYDLDHDN DHEPSSENKE VKSNRKTQFF QWWYFGVCAG
181: SLLGVTVMAY IQDTFGWVIG FAIPTASMLL LIFLFLCGCG VYVYADPDLK AKPFQRILEI
241: IKERVCGRNK ITLVNDHDLN AMELELQDQK PLCNCSNTEA NTTTKSLPDD HKSCKTGFSG
301: LETVKLLLRL LPIWTMLLMF AVIFQQPATF FTKQGMTMKR NIGPNFKIPP ATLQSTITLS
361: IILLMPFYDK ILIPIAKKLT KNEKGISVKE RMGIGMFLSI IAIVIAALVE RKRLKISKMM
421: KTTPNLDPVS ILWLLPQYIL LGISDIFTVV GMQEFFYSEV PVSMRTMGFA LYTSVFGVGS
481: FVSAALISII ETYTSSRGGK HNWFADDMSE ARLDNYYWLL AFTSAISFLM YIVICKHFKS
541: RSDDDDQCDT NC