2.A.17.3.26
Nicotinamine efflux porter of 563 aas and 11 or 12 TMSs. NAET1 and NAET2 function as a nicotianamide (nicotinamide NA)
transporters required for translocation of both iron and copper to
seeds. Chao et al. 2021 showed that NAET1 and NAET2 are predominantly expressed in the shoot
and root vascular tissues and mediate secretion of NA out of cells,
resembling the release of neurotransmitters from animal synaptic
vesicles.
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| Accession Number: | Q9SRI2 |
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| Protein Name: | Protein NRT1/ PTR FAMILY 5.9 |
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| Length: | 563 |
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| Molecular Weight: | 62782.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
nicotinamide |
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1: MDLEQKTRGL SKSCALLIVI AGMERYAFKG VASNLVTYLT DVVKMSNSRA AKTVNTWAGF
61: TSMLPLFSAP LADTYWDRFF TILASSSVYF VGLVGLTWTA FAGSRSATKT ISSYFLYSSL
121: CLVSIGLGVL NPSLQAFGAD QLDHDLDKNF DLSSGDQKDA KATRKTQFFQ LWYFGVCTGS
181: LMGVTVMAYI QDTFGWVLGF AIPGIVIFLS ILVFMSGCGI YVYAPGARLK KKTTTTPFEK
241: ILKFIKGRVV KQRSIYTLAD EKDLDAMELE LEERPLCKCE TEDIETPSTT SKGLEDDESS
301: KTVFSGIDNV KLVIRLFPIW MMLLMFAVIF QLPATFFTKQ GVTMKRNIGS NFKIPPATLQ
361: STITLSIILL MPLYDKILIP ITKRIKKNGT GISVMERMGV GMFLSIIAIV IAAIVERKRL
421: AISQKMKTLP DYDPETVPLS IFWLLPQYIL LGISDIFTVV GMQEFFYSEV PVRMRTMGFA
481: LYTSVFGVGS FVSAALISIV EAYSSSTGDR QNWFADDMSE ARLDKYYWLL ALTSTISFVV
541: YIFLCKFFKS SSDQGDEKEE APK