2.A.18.1.2
Auxin transporter-like protein 3, LAX3, of 470 aas and 11 - 12 TMSs. It is a carrier protein involved in proton-driven auxin influx. It mediates the
formation of auxin gradients from developing leaves (sites of auxin
biosynthesis) to tips by contributing to the loading of auxin in
vascular tissues and facilitating acropetal (base to tip) auxin
transport within inner tissues of the root apex, and basipetal (tip to
base) auxin transport within outer tissues of the root apex. The structures and mechanism of the AUX/LAX transporters involved in auxin import have been reported (Ung et al. 2025).
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| Accession Number: | Q9CA25 |
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| Protein Name: | Auxin transporter-like protein 3 |
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| Length: | 470 |
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| Molecular Weight: | 53305.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
auxin |
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1: MAAEKIETVV AGNYLEMERE EENISGNKKS STKTKLSNFF WHGGSVYDAW FSCASNQVAQ
61: VLLTLPYSFS QLGMMSGILF QLFYGLMGSW TAYLISVLYV EYRTRKEREK FDFRNHVIQW
121: FEVLDGLLGK HWRNLGLIFN CTFLLFGSVI QLIACASNIY YINDKLDKRT WTYIFGACCA
181: TTVFIPSFHN YRIWSFLGLA MTTYTSWYLT IASLLHGQAE DVKHSGPTTM VLYFTGATNI
241: LYTFGGHAVT VEIMHAMWKP QKFKAIYLLA TIYVLTLTLP SASAVYWAFG DKLLTHSNAL
301: SLLPKTGFRD TAVILMLIHQ FITFGFASTP LYFVWEKLIG VHETKSMFKR AMARLPVVVP
361: IWFLAIIFPF FGPINSAVGS LLVSFTVYII PALAHMLTFA PAPSRENAVE RPPRVVGGWM
421: GTYCINIFVV VWVFVVGFGF GGWASMVNFV RQIDTFGLFT KCYQCPPHKP