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Accession Number: | O54701 |
Protein Name: | NCKX2 aka SLC24A2 |
Length: | 670 |
Molecular Weight: | 74657.00 |
Species: | Rattus norvegicus (Rat) [10116] |
Number of TMSs: | 11 |
Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
Substrate | calcium(2+), sodium(1+), potassium(1+) |
Cross database links:
RefSeq: | NP_113931.1 |
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Entrez Gene ID: | 84550 |
Pfam: | PF01699 |
KEGG: | rno:84550 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0008273
F:calcium, potassium:sodium antiporter activity
GO:0046983
F:protein dimerization activity
GO:0015293
F:symporter activity
GO:0006816
P:calcium ion transport
GO:0006813
P:potassium ion transport
GO:0006814
P:sodium ion transport
GO:0055085
P:transmembrane transport
GO:0007601
P:visual perception
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References (1)[1] “Molecular cloning of a novel potassium-dependent sodium-calcium exchanger from rat brain.” Tsoi M.et.al. 9461611
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MDLHQSATVR LLQEWCSHES PSGCRRHYNT RKKLKLIRVI GLVMGLVAVS TVPFSISAFT 61: ETYSQNNRGE ASDVTGPRAA PGHRQRTLLD LNDKIRDYTP QPPASQEDRS ENGTDHAQGD 121: YPKDVFSLEE RRKGAIILHV IGMIYMFIAL AIVCDEFFVP SLTVITEKLG ISDDVAGATF 181: MAAGGSAPEL FTSLIGVFIA HSNVGIGTIV GSAVFNILFV IGMCALFSRE ILNLTWWPLF 241: RDVSFYIVDL IMLIIFFLDN VIMWWESLLL LTAYFAYVVF MKFNVQVERW VKQMINRNKV 301: VKVTVSEAQA KASTAGDKEE PTLPNKPRLQ RGGSSASLHN SLMRNSIFQL MIHTLDPLAE 361: ELGSYGKLKY YDTMTEEGRF REKASILHKI AKKKCQVDEN ERQNGAANHV DYAAEKIELP 421: NSTSTEVEMT PSSEASEPVQ NGNLSHSIEA ADAPQATETA EEDDDQPLSL SWPSNTRKQI 481: TFLIVLPIVF PLWITLPDVR KPASKKFFPI TFFGSITWIA VFSYLMVWWA HQVGETIGIS 541: EEIMGLTILA AGTSIPDLIT SVIVARKGLG DMAVSSSVGS NIFDITVGLP LPWLLYTIIH 601: RFKPVTVSSN GLFCAIVLLF IMLIFVILSI ALCKWRMNKI LGFIMFGLYF AFLVVSVLLE 661: DKVLECPVSI