| |
|---|---|
| Accession Number: | Q71RS6 |
| Protein Name: | NCKX5 |
| Length: | 500 |
| Molecular Weight: | 54888.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | calcium(2+), sodium(1+), potassium(1+) |
Cross database links:
| RefSeq: | NP_995322.1 |
|---|---|
| Entrez Gene ID: | 283652 |
| Pfam: | PF01699 |
| OMIM: |
113750 phenotype 609802 gene |
| KEGG: | hsa:283652 hsa:283652 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0042470
C:melanosome
GO:0015297
F:antiporter activity
GO:0015293
F:symporter activity
GO:0006816
P:calcium ion transport
GO:0006813
P:potassium ion transport
GO:0050896
P:response to stimulus
GO:0006814
P:sodium ion transport
GO:0055085
P:transmembrane transport
GO:0005886
C:plasma membrane
GO:0006811
P:ion transport
| |
References (8)[1] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [2] “SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans.” Lamason R.L.et.al. 16357253 [3] “Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.” Chi A.et.al. 17081065 [4] “A genomewide association study of skin pigmentation in a South Asian population.” Stokowski R.P.et.al. 17999355 | |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MQTKGGQTWA RRALLLGILW ATAHLPLSGT SLPQRLPRAT GNSTQCVISP SSEFPEGFFT 61: RQERRDGGII IYFLIIVYMF MAISIVCDEY FLPSLEIISE SLGLSQDVAG TTFMAAGSSA 121: PELVTAFLGV FITKGDIGIS TILGSAIYNL LGICAACGLL SNTVSTLSCW PLFRDCAAYT 181: ISAAAVLGII YDNQVYWYEG ALLLLIYGLY VLVLCFDIKI NQYIIKKCSP CCACLAKAME 241: RSEQQPLMGW EDEGQPFIRR QSRTDSGIFY EDSGYSQLSI SLHGLSQVSE DPPSVFNMPE 301: ADLKRIFWVL SLPIITLLFL TTPDCRKKFW KNYFVITFFM SAIWISAFTY ILVWMVTITG 361: ETLEIPDTVM GLTLLAAGTS IPDTIASVLV ARKGKGDMAM SNIVGSNVFD MLCLGIPWFI 421: KTAFINGSAP AEVNSRGLTY ITISLNISII FLFLAVHFNG WKLDRKLGIV CLLSYLGLAT 481: LSVLYELGII GNNKIRGCGG