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| Accession Number: | P23936 |
| Protein Name: | LACY aka LacS |
| Length: | 634 |
| Molecular Weight: | 69454.00 |
| Species: | Streptococcus thermophilus [1308] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | alpha-lactose, lactitol |
Cross database links:
| Pfam: | PF00358 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0016301
F:kinase activity
GO:0005351
F:sugar:hydrogen symporter activity
GO:0009401
P:phosphoenolpyruvate-dependent sugar phospho...
GO:0006814
P:sodium ion transport
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References (2)[1] “Lactose transport system of Streptococcus thermophilus: a hybrid protein with homology to the melibiose carrier and enzyme III of phosphoenolpyruvate-dependent phosphotransferase systems.” Poolman B.et.al. 2644191 [2] “Carbohydrate utilization in Streptococcus thermophilus: characterization of the genes for aldose 1-epimerase (mutarotase) and UDPglucose 4-epimerase.” Poolman B.et.al. 1694527
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MEKSKGQMKS RLSYAAGAFG NDVFYATLST YFIMFVTTHL FNTGDPKQNS HYVLLITNII 61: SILRILEVFI DPLIGNMIDN TNTKYGKFKP WVVGGGIISS ITLLLLFTDL GGLNKTNPFL 121: YLVLFGIIYL VMDVFYSIKD IGFWSMIPAL SLDSHEREKM ATFARIGSTI GANIVGVAIM 181: PIVLFFSMTN NSGSGDKSGW FWFAFIVALI GVITSIAVGI GTREVESKIR DNNEKTSLKQ 241: VFKVLGQNDQ LMWLSLGYWF YGLGINTLNA LQLYYFTFIL GDSGKYSILY GLNTVVGLVS 301: VSLFPTLADK FNRKRLFYGC IAVMLGGIGI FSIAGTSLPI ILTAAELFFI PQPLVFLVVF 361: MIISDSVEYG QWKTGHRDES LTLSVRPLID KLGGAMSNWL VSTFAVAAGM TTGASASTIT 421: THQQFIFKLG MFAFPAATML IGAFIVARKI TLTEARHAKI VEELEHRFSV ATSENEVKAN 481: VVSLVTPTTG YLVDLSSVND EHFASGSMGK GFAIKPTDGA VFAPISGTIR QILPTRHAVG 541: IESEDGVIVL IHVGIGTVKL NGEGFISYVE QGDRVEVGQK LLEFWSPIIE KNGLDDTVLV 601: TVTNSEKFSA FHLEQKVGEK VEALSEVITF KKGE