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2.A.21.2.6 High affinity proline-specific Na⁺:proline symporter, PutP (Rivera-Ordaz et al. 2013). Proline is a preferred source of energy for this microaerophilic bacterium. PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid.
Accession Number:	O24896
Protein Name:	Proline permease (PutP)
Length:	496
Molecular Weight:	54081.00
Species:	Helicobacter pylori (strain ATCC 700392 / 26695) [85962]
Number of TMSs:	13
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	sodium(1+), proline

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MGHVVLSTPI VTMFIVYSLL MLYIGFYFYK QNETTEDYFL GDRSMGPVIS ALSAGASDMS 
61:	GWLLMGLPGA LYVGGLINSH IAIGLSLGAL INWVFVAKRL RIYTSVIANS ITISDYFETR 
121:	FSDDKHILRL ISAFVILIFF IFYISSGLVS GAKLFEATFG IQYTYALSIG TLIIVSYTFL 
181:	GGYKAVCWTD LIQGLLMMSA LIVVPIVMII HLGGIGEGIK IIREIKPENL SFLQGSSVVA 
241:	IISSLAWGLG YFGQPHILVR FMSIRSIRDV PKATTIGISW MVISLIGACV MGLLGVAYVH 
301:	KFDLSLEDPE KIFIVMSQLL FNPWITGILL SAILAAVMST ASSQLLVSSS TIAEDFYATI 
361:	FNKDAPQKLV MAISRLSVLG VACIAFFIST DRNASILSIV SYAWAGFGAS FGSVILFSLF 
421:	WSRMTRIGAI AGMLSGASTV ILYDKFGKSF LDIYEIVPGF IVASVAIVVF SLFSSVRTGT 
481:	KEAFETMLKE IESLKH

2.A.21.2.6
High affinity proline-specific Na⁺:proline symporter, PutP (Rivera-Ordaz et al. 2013). Proline is a preferred source of energy for this microaerophilic bacterium. PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid.

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2.A.21.2.6High affinity proline-specific Na+:proline symporter, PutP (Rivera-Ordaz et al. 2013). Proline is a preferred source of energy for this microaerophilic bacterium. PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid.

Cross database links:

External Searches:

Analyze:

2.A.21.2.6
High affinity proline-specific Na⁺:proline symporter, PutP (Rivera-Ordaz et al. 2013). Proline is a preferred source of energy for this microaerophilic bacterium. PutP is efficiently inhibited by the proline analogs, 3,4-dehydro-D,L-proline and L-azetidine-2-carboxylic acid.