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| Accession Number: | P53794 |
| Protein Name: | Sodium/myo-inositol cotransporter |
| Length: | 718 |
| Molecular Weight: | 79694.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), myo-inositol |
Cross database links:
| Entrez Gene ID: | 6526 |
|---|---|
| Pfam: | PF00474 |
| KEGG: | hsa:6526 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005367
F:myo-inositol:sodium symporter activity
GO:0006020
P:inositol metabolic process
GO:0007422
P:peripheral nervous system development
GO:0043576
P:regulation of respiratory gaseous exchange
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References (3)[1] “The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21.” Berry G.T.et.al. 7789985 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MRAVLDTADI AIVALYFILV MCIGFFAMWK SNRSTVSGYF LAGRSMTWVT IGASLFVSNI 61: GSEHFIGLAG SGAASGFAVG AWEFNALLLL QLLGWVFIPI YIRSGVYTMP EYLSKRFGGH 121: RIQVYFAALS LILYIFTKLS VDLYSGALFI QESLGWNLYV SVILLIGMTA LLTVTGGLVA 181: VIYTDTLQAL LMIIGALTLM IISIMEIGGF EEVKRRYMLA SPDVTSILLT YNLSNTNSCN 241: VSPKKEALKM LRNPTDEDVP WPGFILGQTP ASVWYWCADQ VIVQRVLAAK NIAHAKGSTL 301: MAGFLKLLPM FIIVVPGMIS RILFTDDIAC INPEHCMLVC GSRAGCSNIA YPRLVMKLVP 361: VGLRGLMMAV MIAALMSDLD SIFNSASTIF TLDVYKLIRK SASSRELMIV GRIFVAFMVV 421: ISIAWVPIIV EMQGGQMYLY IQEVADYLTP PVAALFLLAI FWKRCNEQGA FYGGMAGFVL 481: GAVRLILAFA YRAPECDQPD NRPGFIKDIH YMYVATGLFW VTGLITVIVS LLTPPPTKEQ 541: IRTTTFWSKK NLVVKENCSP KEEPYQMQEK SILRCSENNE TINHIIPNGK SEDSIKGLQP 601: EDVNLLVTCR EEGNPVASLG HSEAETPVDA YSNGQAALMG EKERKKETDD GGRYWKFIDW 661: FCGFKSKSLS KRSLRDLMEE EAVCLQMLEE TRQVKVILNI GLFAVCSLGI FMFVYFSL