2.A.21.5.8
Sodium-coupled transporter, SLC5A11 or cupcake of 600 aas. A mutant lacking this protein is insensitive to the nutritional value of sugars. It is most similar to mammalian sodium/monocarboxylate co-transporters. It was prominently expressed in 10-13 pairs of R4
neurons of the ellipsoid body in the brain and functioned in these
neurons for selecting appropriate foods (Dus et al. 2013).
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| Accession Number: | Q9VLR8 |
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| Protein Name: | GH19970p |
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| Length: | 600 |
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| Molecular Weight: | 65298.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 13 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+), monocarboxylic acid anion |
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1: MEAVAKKGME NYRFGSVDYA VFLGMIVLST STGIYFGCIK KSKVKLEEAE PTLPTTTPKR
61: RKHDFGSEKM SEYLLGSRNL KVFPVAMSLI ASYISGVTIL GTTSEIYNYG TQYWFIAIAI
121: MLQGIAVSYV YIPVFSALQV GSSYEYLEMR FHSVVRSIAS FMFILDEILF LPFIVYVPAI
181: ALNQVSGINL HVIAVVIVVV CVFYTFVGGI KAVVHTDAWQ VLVMFLSVLA VAILATVYAN
241: GLNVLFDDAA KGGRLIFNNT NPSPYVRHTV WSVLIGGFSY WTSFNAVNQT MVQRYMSLPS
301: LKKARASMAI FTIGVAAFVS VCCYVGLLIY EMYKDCDPLS AGLITHDDQL LPLFVVQSVG
361: HIYGMSGLFI AGIFGAALSS LSVVLNSTSL VILEDIVRGC FKMQPSERAS TILVKSTVIV
421: LGFVALSLVF VLEQLSGILS ICTSMTAIAA GTTFGLFTLG MLVPWANTVG TAVGGIASAL
481: LAGWISFGTQ FTIAAGELNS QKLPVSVEGC VGNVTLRENI WVDEEQVFPL YRLSYHWINP
541: IGVATVIVVG ALVSLVTKPT NMKTLDPDLI SPVIHRFLPK ECFSGRNLHA QAHKNLLNVS