2.A.22.1.12 Sodium-dependent serotonin (5-HT) transporter, SERT, of 666 aas and 12 TMSs. The pharmacology and potential role in the nervous system have been studied (Camicia et al. 2022).
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Accession Number: | XP_024350969.1 |
Protein Name: | XP_024350969.1 Sodium-dependent serotonin transporter [Echinococcus granulosus] |
Length: | 667 |
Molecular Weight: | |
Species: | Echinococcus granulosus [6210] |
Number of TMSs: | 12 |
Substrate |
serotonin |
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1: MQQITIDGAK IKSEVLESGR NAVDVVVEDK SLKSCNLQDP TPSLVEAVVV ETAEAGVTKV
61: ERKREKWDTK VDFLLSVIGF AVDLGNIWRF PYICYQNGGG AFLIPYLLMY IFGGLPLFYL
121: ELALGQFQRS GCISVWSRIC PFFTGLGYGI CIIASYTAWY YNTVISWALF YMFDSMRLRL
181: PWDSCDNWWN TPKTCITVYQ KLVTGANSSG IADSDASNTL HAVNTTGYYS STEQYFYNRV
241: LQIQFSDGFN KLGTIRWEVA LCLLAVFTLV YFALWKGVKS SGKAVWITAT LPYVILFILL
301: IRGLTLRGSL MGIQYYLLPD FGRLKSIEVW NAAASQIFFS LGPGFGVLLA LASYNRFRNN
361: CYYDAMLTSA INCGTSFLSG FVVFSVLGHM CYRMNRTMDT VANEGPSLVF IAYPEAIATL
421: PGSTFWAIIF MLMLITLGLD STFGGLEAII TALLDRWPKL RKRREIVVLI MIIYCYVGAL
481: PTTTNGGYYI LTLFDTYGAP FSILFIVFCE CVALCWCYGV GRFTRDIESM LGFKPGWFWR
541: ICWAVISPAF MLGIFILNIT FFRPPEITVM GKTVRADTWV HVVSWMLVFS SLVTIPIFAV
601: VTFCNARGSF KERLKSLFTP GIRPSFSDFH VHPNSHKKQE IKDKNEEQVA KSAEAVDDTQ
661: SEGDEG