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| Accession Number: | P28573 |
| Protein Name: | NTPR aka SLC6A7 |
| Length: | 637 |
| Molecular Weight: | 71091.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), proline |
Cross database links:
| RefSeq: | NP_446448.2 |
|---|---|
| Entrez Gene ID: | 117100 |
| Pfam: | PF00209 |
| KEGG: | rno:117100 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0015193
F:L-proline transmembrane transporter activity
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0006836
P:neurotransmitter transport
GO:0015824
P:proline transport
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References (1)[1] “Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain.” Fremeau R.T. Jr.et.al. 1350201
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKKLQEAHLR KPVTPDLLMT PSDQGDVDLD VDFAADRGNW TGKLDFLLSC IGYCVGLGNV 61: WRFPYRAYTN GGGAFLVPYF LMLAICGIPL FFLELSLGQF SSLGPLAVWK ISPLFKGAGA 121: AMLLIVGLVA IYYNMIIAYV LFYLFASLTS NLPWEHCGNW WNTERCLEHR GPKDGNGALP 181: LNLSSTVSPS EEYWSRYVLH IQGSQGIGRP GEIRWNLCLC LLLAWVIVFL CILKGVKSSG 241: KVVYFTATFP YLILLMLLVR GVTLPGAWKG IQFYLTPQFH HLLSSKVWIE AALQIFYSLG 301: VGFGGLLTFA SYNTFHQNIY RDTFIVTLGN AITSILAGFA IFSVLGYMSQ ELGVPVDQVA 361: KAGPGLAFVI YPQAMTMLPL SPFWSFLFFF MLLTLGLDSQ FAFLETIVTA VTDEFPYYLR 421: PKKAVFSGLI CVAMYLMGLI LTTDGGMYWL VLLDDYSASF GLMVVVITTC LAVTRVYGIQ 481: RFCRDIHMML GFKPGLYFRA CWLFLSPATL LALLVYSIVK YQPSEYGSYR FPAWAELLGI 541: LMGLLSCLMI PAGMLVAVLR EEGSLWERLQ QASRPAIDWG PSLEENRTGM YVATLAGSQS 601: PKPLMVHMRK YGGITSFENT AIEVDREIAE EEEESMM