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| Accession Number: | Q99884 |
| Protein Name: | Sodium-dependent proline transporter |
| Length: | 636 |
| Molecular Weight: | 70911.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), proline |
Cross database links:
| Entrez Gene ID: | 6534 |
|---|---|
| Pfam: | PF00209 |
| KEGG: | hsa:6534 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005624
C:membrane fraction
GO:0015193
F:L-proline transmembrane transporter activity
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0015824
P:proline transport
GO:0055085
P:transmembrane transport
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References (3)[1] “Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes.” Shafqat S.et.al. 7651355 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKKLQGAHLR KPVTPDLLMT PSDQGDVDLD VDFAAHRGNW TGKLDFLLSC IGYCVGLGNV 61: WRFPYRAYTN GGGAFLVPYF LMLAICGIPL FFLELSLGQF SSLGPLAVWK ISPLFKGAGA 121: AMLLIVGLVA IYYNMIIAYV LFYLFASLTS DLPWEHCGNW WNTELCLEHR VSKDGNGALP 181: LNLTCTVSPS EEYWSRYVLH IQGSQGIGSP GEIRWNLCLC LLLAWVIVFL CILKGVKSSG 241: KVVYFTATFP YLILLMLLVR GVTLPGAWKG IQFYLTPQFH HLLSSKVWIE AALQIFYSLG 301: VGFGGLLTFA SYNTFHQNIY RDTFIVTLGN AITSILAGFA IFSVLGYMSQ ELGVPVDQVA 361: KAGPGLAFVV YPQAMTMLPL SPFWSFLFFF MLLTLGLDSQ FAFLETIVTA VTDEFPYYLR 421: PKKAVFSGLI CVAMYLMGLI LTTDGGMYWL VLLDDYSASF GLMVVVITTC LAVTRVYGIQ 481: RFCRDIHMML GFKPGLYFRA CWLFLSPATL LALMVYSIVK YQPSEYGSYR FPPWAELLGI 541: LMGLLSCLMI PAGMLVAVLR EEGSLWERLQ QASRPAMDWG PSLEENRTGM YVATLAGSQS 601: PKPLMVHMRK YGGITSFENT AIEVDREIAE EEESMM