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| Accession Number: | Q9W4C5 |
| Protein Name: | Sodium-dependent nutrient amino acid transporter 1 |
| Length: | 641 |
| Molecular Weight: | 71762.00 |
| Species: | Drosophila melanogaster (Fruit fly) [7227] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), alpha-amino acid |
Cross database links:
| Entrez Gene ID: | 31457 |
|---|---|
| Pfam: | PF00209 |
| KEGG: | dme:Dmel_CG3252 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0042943
F:D-amino acid transmembrane transporter activity
GO:0015179
F:L-amino acid transmembrane transporter activity
GO:0005326
F:neurotransmitter transporter activity
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0015175
F:neutral amino acid transmembrane transporter activity
GO:0005283
F:sodium:amino acid symporter activity
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References (5)[1] “The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions.” Miller M.M.et.al. 18718864 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MELKGVQPSN GSSNGSGNGA TNAASTEKTD AEKPTAERTN WGNGLEFLMS CISVSVGLGN 61: VWRFPFTAYE NGGGAFLIPY IIVLFLIGKP MYYLEMIMGQ FTSQGTVKIW SVVPGFVGVG 121: YGQAFGTICI ISYYSSLLAL TLYYLFVSFQ SELPWSYCRD EWTNCVNSRP QEYVDNLLTG 181: VSLANESARN LSGIVANDET EKLQSSSELY FLNVVIKEKL DISDGVGDPD WKLTLALFVA 241: WVVIFLVIMR GVKSSGKAAY FLALFPYVVL FVLLIRAVTL EGARDGILFF LEPQWGELLN 301: PTVWKEAVVQ CFFSLAVGSG PIIMFASYNR FDHGIYRDAM IVTTLDTLTS LLGGITIFAI 361: LGNLAHNLQI ENIRDVVRSG TGLAFISYPD AISKFQAVPQ LFSVLFFFML FVLGIGSIVA 421: LQSTIVTIIC DQFKGWKYWK VALTTSVCGF LMGLVYVTPG GQWILTLVDF YGGTYVVFIL 481: AIFELAGIVW VYGLQNFCDD IEFMCNRRVS LYWRVCWSFF TPVMMIIIFI YSMVTIEPIK 541: YSELYFPEAA NIAGWLLFAI GAAQFPLWGL WYISRHPQGT YWKSLKASLK PSDRWGPANP 601: EIRREWVIFK NQKAAQRATQ KDTSKLGFFW RKVANFCGSN K