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| Accession Number: | P28572 |
| Protein Name: | NTGL aka GlyT1c aka SLC6A9 |
| Length: | 638 |
| Molecular Weight: | 71061.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, sodium(1+), glycine |
Cross database links:
| RefSeq: | NP_446270.1 |
|---|---|
| Entrez Gene ID: | 116509 |
| Pfam: | PF00209 |
| KEGG: | rno:116509 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0015187
F:glycine transmembrane transporter activity
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0005515
F:protein binding
GO:0005283
F:sodium:amino acid symporter activity
GO:0006865
P:amino acid transport
GO:0006836
P:neurotransmitter transport
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References (5)[1] “Cloning, expression, and localization of a rat brain high-affinity glycine transporter.” Guastella J.et.al. 1353889 [2] “Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors.” Smith K.E.et.al. 1534013 [3] “Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.” Borowsky B.et.al. 8494645 [4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [5] “Analysis of a gene encoding two glycine transporter variants reveals alternative promoter usage and a novel gene structure.” Borowsky B.et.al. 9786914
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAVAHGPVAT SSPEQNGAVP SEATKKDQNL TRGNWGNQIE FVLTSVGYAV GLGNVWRFPY 61: LCYRNGGGAF MFPYFIMLVF CGIPLFFMEL SFGQFASQGC LGVWRISPMF KGVGYGMMVV 121: STYIGIYYNV VICIAFYYFF SSMTHVLPWA YCNNPWNTPD CAGVLDASNL TNGSRPTALS 181: GNLSHLFNYT LQRTSPSEEY WRLYVLKLSD DIGDFGEVRL PLLGCLGVSW VVVFLCLIRG 241: VKSSGKVVYF TATFPYVVLT ILFVRGVTLE GAFTGIMYYL TPKWDKILEA KVWGDAASQI 301: FYSLGCAWGG LITMASYNKF HNNCYRDSVI ISITNCATSV YAGFVIFSIL GFMANHLGVD 361: VSRVADHGPG LAFVAYPEAL TLLPISPLWS LLFFFMLILL GLGTQFCLLE TLVTAIVDEV 421: GNEWILQKKT YVTLGVAVAG FLLGIPLTSQ AGIYWLLLMD NYAASFSLVV ISCIMCVSIM 481: YIYGHRNYFQ DIQMMLGFPP PLFFQICWRF VSPTIIFFIL IFTVIQYRPI TYNHYQYPGW 541: AVAIGFLMAL SSVICIPLYA LFQLCRTDGD TLLQRLKNAT KPSRDWGPAL LEHRTGRYAP 601: TTTPSPEDGF EVQPLHPDKA QIPIVGSNGS SRLQDSRI