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|---|---|
| Accession Number: | Q9VR07 |
| Protein Name: | Sodium- and chloride-dependent GABA transporter ine |
| Length: | 943 |
| Molecular Weight: | 103636.00 |
| Species: | Drosophila melanogaster (Fruit fly) [7227] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, sodium(1+), gamma-aminobutyric acid |
Cross database links:
| Entrez Gene ID: | 33659 |
|---|---|
| Pfam: | PF00209 |
| KEGG: | dme:Dmel_CG1544 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0005034
F:osmosensor activity
GO:0009881
F:photoreceptor activity
GO:0042066
P:perineurial glial growth
GO:0047484
P:regulation of response to osmotic stress
GO:0019226
P:transmission of nerve impulse
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References (10)[1] “Identification and characterization of inebriated, a gene affecting neuronal excitability in Drosophila.” Stern M.et.al. 1334137 [2] “Drosophila rosA gene, which when mutant causes aberrant photoreceptor oscillation, encodes a novel neurotransmitter transporter homologue.” Burg M.G.et.al. 10876650 [3] “A neurotransmitter transporter encoded by the Drosophila inebriated gene.” Soehnge H.et.al. 8917579 [4] “The genome sequence of Drosophila melanogaster.” Adams M.D.et.al. 10731132 [5] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.” Misra S.et.al. 12537572 [6] “A Drosophila full-length cDNA resource.” Stapleton M.et.al. 12537569 [7] “Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.” Yager J.et.al. 11517334 [8] “The Drosophila inebriated-encoded neurotransmitter/osmolyte transporter: dual roles in the control of neuronal excitability and the osmotic stress response.” Huang X.et.al. 11861562 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAENKDVSQV LNTTPDQVVI NRAPPTGLAP LRHSQLSDSG AESCYEGDEQ ARLIRSSSSR 61: AHKFIIIPAT PGTPPGSGAV AGPLPFRQTS STTSLAAMAA ALHKQSPLRH TSVRTRPSSE 121: VLQPGQVLAN QPTAAVSTST VTFTIDDCNE EGDAIPAAAS VPAPVTMPAI SPTPATLTCT 181: TTTTMAGDSV AVSPLSMELK SRLGSHHSSM RSVVSGYLPG LSDSSGNLVG GVSMATSGLQ 241: APNPLYMQPQ ASLSGSSYHF HELAGNQIYS DVTSVRSLAS IGIGSTDGRK LVIRRVPTTA 301: NELFDMVNPQ TPPPLGVDDD DSYLDMSDET AQLKPRQQHW ANKMQFVLAC IGYSVGLGNV 361: WRFPYMCYKS GGGVFLVPYC IILFICSIPL LFMELSVGQY TGRGPIGALG QLCPLFKGAG 421: LASVVVSFLM STYYSVIIGY SIYYFFTSFK TEMPWIDCNN RWNTPDCWVP QRKGINASAP 481: DTSRTPSEEF FENKVLQISG GLEYPGMMRW ELFACLICAW LMVYFATWKS IKSSAKVRYF 541: TATFPFVLII ILMVRAVTLD GAAEGLRFFF RPKWSELKNA NVWINAASQN FNSLGITFGS 601: MISFASYNKY NNNILRDTVA VSAVNMITSL LVGIFAFSTL GNLALEQNTN VRDVIGDGPG 661: MIFVVYPQAM AKMPYAQLWA VMFFFMLLCL GLNSQFAIVE VVVTSIQDGF PRWIKRHLGY 721: HEIVVLFVCV ISCLFGMPNI IQGGIYYFQL MDHYAASVTI MFLAFCQMIA IAWFYGTGRL 781: SKNVKQMTGK APSFYLRSCW LVLGPCLLFA IWVLSLINYH EPTYHNGRYT YPDWAYGIGW 841: MFASFSLICI PGYAVINFLR SSGDTFWERI RNTLRPNIYE CKICGEHHCE HDYPEQEQFM 901: LAQEMATVYK PTNPHLLNLG QKCGYNAMQA SPSHAEAGGP CGQ