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| Accession Number: | P28570 |
| Protein Name: | NTCH aka SLC6A8 |
| Length: | 635 |
| Molecular Weight: | 70632.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, sodium(1+), creatine |
Cross database links:
| RefSeq: | NP_059044.1 |
|---|---|
| Entrez Gene ID: | 50690 |
| Pfam: | PF00209 |
| KEGG: | rno:50690 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0015220
F:choline transmembrane transporter activity
GO:0005309
F:creatine:sodium symporter activity
GO:0015881
P:creatine transport
GO:0006836
P:neurotransmitter transport
GO:0006814
P:sodium ion transport
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References (1)[1] “Primary structure and functional expression of a choline transporter expressed in the rat nervous system.” Mayser W.et.al. 1633856
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAKKSAENGI YSVSGDEKKG PLIVSGPDGA PSKGDGPAGL GAPSSRLAVP PRETWTRQMD 61: FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 121: INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 181: CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSTGLEVPGA LNWEVTLCLL 241: ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL 301: GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF 361: SILGFMATEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV 421: GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG 481: TTLLWQAFWE CVVVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNVV 541: YYKPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG 601: LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM