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| Accession Number: | Q5J2D5 |
| Protein Name: | GABA transporter protein |
| Length: | 610 |
| Molecular Weight: | 69313.00 |
| Species: | Caenorhabditis elegans [6239] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | chloride, sodium(1+), indole-3-butyric acid |
Cross database links:
| RefSeq: | NP_505873.2 |
|---|---|
| Entrez Gene ID: | 191770 |
| Pfam: | PF00209 |
| KEGG: | cel:T03F7.1 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0006836
P:neurotransmitter transport
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References (3)[1] “A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function.” Jiang G.et.al. 15542610 [2] “Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins.” Kaji H.et.al. 17761667 [3] “Genome sequence of the nematode C. elegans: a platform for investigating biology.” The C. elegans sequencing consortiumet.al. 9851916
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MVEATSVAER EQWSSWADFI MSCIGYAIGL GNVWRFPYLC YQNGGGAFLI PYCISLVFCG 61: APLFILETSW GQLMSVGGLG MFKICPIFKG VGIAAAVMAF WLNIYYIVVL SWAATYLYNS 121: FTMSDVPWKN CDHAWNTPNC RSEYVKIPCD SNRTIAEFFN VKVLTHDHIH EYKKQFFVGE 181: KMNWTVCSAA DLSVVSPVKE FWNHRVLGIS SGLENPGGIR WDLALFLLLV WIICYLCIFK 241: GVKWTGKVVY ITASFPYMML FCLLIRGLTL EGAGVGLEFY LKPDFSKLLE SKVWVDAVTQ 301: VFFSYGLGLG ALVALGSYNK FNNNVYKQAL TVCFVNSGTS VFAGFVIFSF IGFMATQQEK 361: SVAEVAQAGP GLLFLAYPSG ILQLPYTQFW SCLFFLMVLF LGVDSQFCTM EGFFTAIIDE 421: FPQIRRKKYG REIFVGVICV ISYLIGLTTV TEGGFYVFQL FDFYAASGWA LLWLLFFECI 481: AISWSLGIDR WYEHMKSMIG YYPSAWWKFC WVFATPSVCF GVLLFGLIKY QPLRIDAYNY 541: DYPVWGHIFG WFLSLSSMLC IPGYAIWIWF KTPGTVQEKI KLLCRPDIEI KGAMENAENL 601: ELVEDFQNAI