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|---|---|
| Accession Number: | Q96N87 |
| Protein Name: | Sodium- and chloride-dependent transporter XTRP2 |
| Length: | 628 |
| Molecular Weight: | 70925.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| RefSeq: | NP_872438.2 |
|---|---|
| Entrez Gene ID: | 348932 |
| Pfam: | PF00209 |
| OMIM: |
610300 gene |
| KEGG: | hsa:348932 hsa:348932 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0006865
P:amino acid transport
GO:0006836
P:neurotransmitter transport
GO:0005886
C:plasma membrane
GO:0006811
P:ion transport
GO:0006970
P:response to osmotic stress
GO:0055085
P:transmembrane transport
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References (10)[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Mutations in SLC6A19, encoding B(0)AT1, cause Hartnup disorder.” Kleta R.et.al. 15286787 [4] “A nonsense polymorphism (Y319X) of the solute carrier family 6 member 18 (SLC6A18) gene is not associated with hypertension and blood pressure in Japanese.” Eslami B.et.al. 16340170 [5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [6] “The DNA sequence and comparative analysis of human chromosome 5.” Schmutz J.et.al. 15372022 [7] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [8] “Mutations in SLC6A19, encoding B(0)AT1, cause Hartnup disorder.” Kleta R.et.al. 15286787 [9] “A nonsense polymorphism (Y319X) of the solute carrier family 6 member 18 (SLC6A18) gene is not associated with hypertension and blood pressure in Japanese.” Eslami B.et.al. 16340170 [10] “Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters.” Broer S.et.al. 19033659
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAHAPEPDPA ACDLGDERPK WDNKAQYLLS CIGFAVGLGN IWRFPYLCQT YGGGAFLIPY 61: VIALVFEGIP IFHVELAIGQ RLRKGSVGVW TAISPYLSGV GLGCVTLSFL ISLYYNTIVA 121: WVLWYLLNSF QHPLPWSSCP PDLNRTGFVE ECQGSSAVSY FWYRQTLNIT ADINDSGSIQ 181: WWLLICLAAS WAVVYMCVIR GIETTGKVIY FTALFPYLVL TIFLIRGLTL PGATKGLIYL 241: FTPNMHILQN PRVWLDAATQ IFFSLSLAFG GHIAFASYNS PRNDCQKDAV VIALVNRMTS 301: LYASIAVFSV LGFKATNDYE HCLDRNILSL INDFDFPEQS ISRDDYPAVL MHLNATWPKR 361: VAQLPLKACL LEDFLDKSAS GPGLAFVVFT ETDLHMPGAP VWAMLFFGML FTLGLSTMFG 421: TVEAVITPLL DVGVLPRWVP KEALTGLVCL VCFLSATCFT LQSGNYWLEI FDNFAASLNL 481: LMLAFLEVVG VVYVYGMKRF CDDIAWMTGR RPSPYWRLTW RVVSPLLLTI FVAYIILLFW 541: KPLRYKAWNP KYELFPSRQE KLYPGWARAA CVLLSLLPVL WVPVAALAQL LTRRRRTWRD 601: RDARPDTDMR PDTDTRPDTD MRPDTDMR