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|---|---|
| Accession Number: | Q9GZN6 |
| Protein Name: | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 |
| Length: | 736 |
| Molecular Weight: | 82200.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| Entrez Gene ID: | 28968 |
|---|---|
| Pfam: | PF00209 |
| KEGG: | hsa:28968 hsa:28968 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005622
C:intracellular
GO:0005328
F:neurotransmitter:sodium symporter activity
GO:0005326
F:neurotransmitter transporter activity
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References (8)[1] “Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family.” Farmer M.K.et.al. 11112352 [2] “Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.” Wiemann S.et.al. 11230166 [3] “Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.” Yu L.-R.et.al. 17924679 [4] “Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.” Varela I.et.al. 21248752 [5] “Cloning and characterization of human NTT5 and v7-3: two orphan transporters of the Na(+)/Cl(-)-dependent neurotransmitter transporter gene family.” Farmer M.K.et.al. 11112352 [6] “Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.” Wiemann S.et.al. 11230166 [7] “Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.” Yu L.-R.et.al. 17924679 [8] “Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.” Varela I.et.al. 21248752
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKTEAQPSTS LLANTSWTGT VISDSVPGSQ TWEDKGSLTR SATSWTSEAQ VSAARVAEAQ 61: ARTSQPKQIS VLEALTASAL NQKPTHEKVQ MTEKKESEVL LARPFWSSKT EYILAQVGFS 121: MKPSCLWRFA YLWLNSGGCS FAAIYIFMLF LVGVPLLFLE MAAGQSMRQG GMGVWKIIAP 181: WIGGVGYSSF MVCFILGLYF NVVNSWIIFY MSQSFQFPVP WEKCPLTMNS SGFDPECERT 241: TPSIYFWYQQ ALKASDRIED GGSPVYSLVL PFFLCWCLVG AFMINGLKST GKVIYVLVLL 301: PCFIIVGFFI RTLLLEGAKF GLQQLVVAKI SDVYNMSVWS LAGGQVLSNT GIGLGSVASL 361: ASYMPQSNNC LSDAFLVSVI NLLTLLVFTS FNFCVLGFWA TVITHRCCER NAEILLKLIN 421: LGKLPPDAKP PVNLLYNPTS IYNAWLSGLP QHIKSMVLRE VTECNIETQF LKASEGPKFA 481: FLSFVEAMSF LPPSVFWSFI FFLMLLAMGL SSAIGIMQGI ITPLQDTFSF FRKHTKLLIV 541: GVFLLMFVCG LFFTRPSGSY FIRLLSDYWI VFPIIVVVVF ETMAVSWAYG ARRFLADLTI 601: LLGHPISPIF GWLWPHLCPV VLLIIFVTMM VHLCMKPITY MSWDSSTSKE VLRPYPPWAL 661: LLMITLFAIV ILPIPAYFVY CRIHRIPFRP KSGDGPMTAS TSLPLSHQLT PSKEVQKEEI 721: LQVDETKYPS TCNVTS