2.A.22.7.1
Amino acid/GABA uptake porter, NSS3, of 1439 aas and 16 TMSs with an N-terminal hydrophilic region (residues 1 - 480), + 3 TMSs (residues 481 - 590), + 10 TMSs (residues 720 - 1170) + 3 TMSs (residues 1290 - 1430) (Wunderlich 2022).
|
| Accession Number: | Q8II40 |
|---|
| Protein Name: | Amino acid transporter, putative |
|---|
| Length: | 1439 |
|---|
| Molecular Weight: | 174052.00 |
|---|
| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
|---|
| Number of TMSs: | 16 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
amino acid, gamma-aminobutyric acid |
|---|
1: MGTPDNTDET YNITLHHLER ERKMRNKLDV SHNKDPFDLK LYLYNACLNF SNTDIYQEYI
61: NRLSINSYNN CDYDQIKRSC YISNKDFLKY YNYNFYDNDF VLEMDNHTED TSSSYHLNEM
121: KELEELSEFV IHKMKKIKKE FVKNDISRKR RSEICKCTRN VLWSKEKRNT ENNNSLSISY
181: NNNNNNLLST NFQKDNSHLF STLIEKEKKN KNKKKNNFLY LSHIGDIKNE ESIYHNEYHI
241: TSNYLPYYFF MKKNNIFSKT CNQSREHSSI SYHMDDFFLK CQSINRMKLK NSGNSYYFCM
301: LQNIEEAQND PIVEMYYKYL DDVIKKKSRG NIYDNYSLCS MLDNTKKKKK KKKIKKDKMS
361: KNKEMYDKIN IYNNTNILNT SNHSSYETEI YSNNIINIDE ENTLENYYID MEIYNNLHTS
421: DNNKKKDITN KINEPNTLVQ INKKKKNIKR LSSVEMDIYI KTMMINEKIK SNQQRIDKRD
481: KWNALYQFMF SCIGASLSIY FYLDLPLLRT KFDYILTCVI IFCSYIFIGL PLLQIELSLG
541: QLSQGCILNS LSFLKKKIKG IGLLSFIILF YLLMRNMSYS ITTLVIAVNS VWRPLPWDIK
601: ECEKINKQQT CVSDIKCRWI EWKEKDDIKT FKMYDNIQYK DLSQNGLLDK HPYRHNLSYH
661: NPSNDKLQLD ISHVSEKEHN EDLNIFMYSK KREPVQNNSH SCVSISTMEI ILFFTKNISF
721: VWKILSLFVI LILLYFLLKI ETMSLNQSLH YILSISFIIV LLQILILYYK LEPKEYTQNE
781: NMAIKYNTCI FFSKEYFLHI NFYLIIKIIC LVLFSVNCST GINYIFSSYT NIGDNIIKQS
841: YYIILGSFIV TITYLTYYYL CILHIHNNNN NKNNINVYDD EYILNYFIDY YNILPINIAH
901: IVQEKKNIIF SFLKNNVKYH YIPHQIIIYL LVLSKYIPFS NMMCFLYFLS SLLVLLITIT
961: IHIKVIIITL KECRKFRKIN KKKFIIYIII IYFFASLLNI FFFTSYISYW FNYNIIYNIY
1021: LFIVFFQMIS ITWVYGSEYT SKKINHQKIY FYYSIHFFIS ILLLPIMIYP YYYNIYNKRY
1081: VFFILLTLNI VQFISVHIYF LYSIKLPKKT FKQKISYLYI SNMNLLKRRL NNIFYGKYRK
1141: YDTQTNKENN NIKTNKIYKC HILQKLTPMW CFLLKYFITT IFIFLLISNL LHHVYENNKL
1201: YHKLKQNNYL LSYKSQYYLH NINQSYIKYN NDEFYNLRKV HDKNEKTEKK KSIQKNNNIQ
1261: NILSNNTIHE YPKMGYGQDK DNYIYHHIYM NTLIYIIVTI LFIIFLLLFS FFSYFKHKKF
1321: NIFINSPNKL YNINDIQKKI RKPVKFLYTR SFFFFEELLP VQYIMPSYIW THINKHLKTE
1381: SFIQSLKKEY ENCENIIDKK FLFYNKAQFE SYILGLICQG SRLEHFTQKK KKKRIDKNE