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|---|---|
| Accession Number: | O00341 |
| Protein Name: | Excitatory amino acid transporter 5 |
| Length: | 560 |
| Molecular Weight: | 60658.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | glutamate(2-) |
Cross database links:
| Entrez Gene ID: | 6512 |
|---|---|
| Pfam: | PF00375 |
| KEGG: | hsa:6512 hsa:6512 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005313
F:L-glutamate transmembrane transporter activity
GO:0017153
F:sodium:dicarboxylate symporter activity
GO:0006835
P:dicarboxylic acid transport
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References (8)[1] “Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance.” Arriza J.L.et.al. 9108121 [2] “The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G.et.al. 16710414 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “The consensus coding sequences of human breast and colorectal cancers.” Sjoeblom T.et.al. 16959974 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MVPHAILARG RDVCRRNGLL ILSVLSVIVG CLLGFFLRTR RLSPQEISYF QFPGELLMRM 61: LKMMILPLVV SSLMSGLASL DAKTSSRLGV LTVAYYLWTT FMAVIVGIFM VSIIHPGSAA 121: QKETTEQSGK PIMSSADALL DLIRNMFPAN LVEATFKQYR TKTTPVVKSP KVAPEEAPPR 181: RILIYGVQEE NGSHVQNFAL DLTPPPEVVY KSEPGTSDGM NVLGIVFFSA TMGIMLGRMG 241: DSGAPLVSFC QCLNESVMKI VAVAVWYFPF GIVFLIAGKI LEMDDPRAVG KKLGFYSVTV 301: VCGLVLHGLF ILPLLYFFIT KKNPIVFIRG ILQALLIALA TSSSSATLPI TFKCLLENNH 361: IDRRIARFVL PVGATINMDG TALYEAVAAI FIAQVNNYEL DFGQIITISI TATAASIGAA 421: GIPQAGLVTM VIVLTSVGLP TDDITLIIAV DWALDRFRTM INVLGDALAA GIMAHICRKD 481: FARDTGTEKL LPCETKPVSL QEIVAAQQNG CVKSVAEASE LTLGPTCPHH VPVQVEQDEE 541: LPAASLNHCT IQISELETNV