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|---|---|
| Accession Number: | O05256 |
| Protein Name: | YufR aka MAEN |
| Length: | 448 |
| Molecular Weight: | 47824.00 |
| Species: | Bacillus subtilis [1423] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), malate(2-) |
Cross database links:
| RefSeq: | NP_391036.1 |
|---|---|
| Entrez Gene ID: | 938855 |
| Pfam: | PF03390 |
| KEGG: | bsu:BSU31580 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0008514
F:organic anion transmembrane transporter act...
GO:0015293
F:symporter activity
GO:0015711
P:organic anion transport
GO:0006814
P:sodium ion transport
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References (4)[1] “Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).” Oudega B.et.al. 9274030 [2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F.et.al. 9384377 [3] “Bacillus subtilis YqkI is a novel malic/Na+-lactate antiporter that enhances growth on malate at low protonmotive force.” Wei Y.et.al. 10903309 [4] “The Bacillus subtilis YufLM two-component system regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium.” Tanaka K.et.al. 12949159
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGAIPKTGTI SPEQKDSQEK NLFQKIWSWE IGVIPLPLYT VLAVIIILAA YYNELPANML 61: GGFAIIMILG VFLGDIGQRI PILKDIGGPA ILSLFVPSFL VFYNVLNSTS LDAVTNLMKT 121: SNFLYFYIAC LVVGSILGMN RIVLIQGFIR MFVPLVAGTI AAVAAGILVG FIFGYSAYDS 181: FFFVVVPIIA GGIGEGILPL SIAYSQILGS SADVFVSQLV PAAIIGNVFA IICAALMKKL 241: GDKRPDLNGN GRLVKSKKAN EIFNQKEAEA KIDFKLMGAG VLLACTFFIF GGLLEKFIFI 301: PGAILMIISA AAVKYANILP KKMEEGAYQL YKFISSSFTW PLMVGLGILF IPLDDVASVI 361: SIPFVIICIS VVIAMIGSGY FVGKLMNMYP VESAIVTCCH SGLGGTGDVA ILSASGRMGL 421: MPFAQISTRL GGAGTVICAT VLLRFFTS