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2.A.29.2.1
Oxoglutarate/malate antiporter. Also transports porphyrin derivatives: Fe-protoporphyrin IX, coproporphyrin III, hemin, etc. (Kabe et al., 2006). Plays roles in the malate-aspartate shuttle, the oxoglutarate-isocitrate shuttle and gluconeogenesis.  Functional residues have been identified (Cappello et al. 2007).

Accession Number:P22292
Protein Name:M2OM aka SLC25A11 aka SLC20A4
Length:314
Molecular Weight:34172.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate coproporphyrin III, hemin, malate(2-), 2-oxoglutaric acid

Cross database links:

RefSeq: NP_777096.1   
Entrez Gene ID: 282523   
Pfam: PF00153   
KEGG: bta:282523   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0005488 F:binding
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier.”  Iacobazzi V.et.al.   1457818
[2] “Sequence of the bovine 2-oxoglutarate/malate carrier protein: structural relationship to other mitochondrial transport proteins.”  Runswick M.J.et.al.   2271695
[3] “Characterization of 954 bovine full-CDS cDNA sequences.”  Harhay G.P.et.al.   16305752

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MAATASPGAS GMDGKPRTSP KSVKFLFGGL AGMGATVFVQ PLDLVKNRMQ LSGEGAKTRE 
61:	YKTSFHALIS ILRAEGLRGI YTGLSAGLLR QATYTTTRLG IYTVLFERLT GADGTPPGFL 
121:	LKAVIGMTAG ATGAFVGTPA EVALIRMTAD GRLPVDQRRG YKNVFNALFR IVQEEGVPTL 
181:	WRGCIPTMAR AVVVNAAQLA SYSQSKQFLL DSGYFSDNIL CHFCASMISG LVTTAASMPV 
241:	DIVKTRIQNM RMIDGKPEYK NGLDVLVKVV RYEGFFSLWK GFTPYYARLG PHTVLTFIFL 
301:	EQMNKAYKRL FLSG