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| Accession Number: | O89035 |
| Protein Name: | Mitochondrial dicarboxylate carrier |
| Length: | 286 |
| Molecular Weight: | 31455.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 2 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | fumarate(2-), oxaloacetate(2-), 2-oxoglutarate(2-), malate(2-), succinate(2-) |
Cross database links:
| RefSeq: | NP_596909.1 |
|---|---|
| Entrez Gene ID: | 170943 |
| Pfam: | PF00153 |
| KEGG: | rno:170943 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0015297
F:antiporter activity
GO:0005488
F:binding
GO:0015140
F:malate transmembrane transporter activity
GO:0015114
F:phosphate transmembrane transporter activity
GO:0015141
F:succinate transmembrane transporter activity
GO:0015116
F:sulfate transmembrane transporter activity
GO:0015117
F:thiosulfate transmembrane transporter activity
GO:0015743
P:malate transport
GO:0006839
P:mitochondrial transport
GO:0006817
P:phosphate transport
GO:0015744
P:succinate transport
GO:0008272
P:sulfate transport
GO:0015709
P:thiosulfate transport
GO:0055085
P:transmembrane transport
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References (4)[1] “Identification by bacterial expression and functional reconstitution of the yeast genomic sequence encoding the mitochondrial dicarboxylate carrier protein.” Palmieri L.et.al. 8985166 [2] “The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans.” Fiermonte G.et.al. 9733776 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAEARTSRWY FGGLASCGAA CCTHPLDLLK VHLQTQQEVK LRMTGMALQV VRTDGFLALY 61: NGLSASLCRQ MTYSLTRFAI YETMRDYMTK DSQGPLPFYS KVLLGGISGL TGGFVGTPAD 121: LVNVRMQNDM KLPLSQRRNY SHALDGLYRV AREEGLKKLF SGATMASSRG ALVTVGQLSC 181: YDQAKQLVLS TGYLSDNIFT HFLSSFIAGG CATFLCQPLD VLKTRLMNSK GEYQGVFHCA 241: VETAKLGPQA FFKGLVPAGV RLVPHTVLTF MFLEQLRKHF GIKVAT