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2.A.3.1.15
Serine/Threonine transport protein, YifK of 461 aas and 12 TMSs in a probable 6 + 6 TMS arrangement (Khozov et al. 2023).

Accession Number:P27837
Protein Name:Probable transport protein YifK
Length:461
Molecular Weight:50399.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 945400   
Pfam: PF00324   
KEGG: eco:b3795   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (5)

[1] “Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.”  Daniels D.L.et.al.   1379743
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.”  Riley M.et.al.   16397293
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MADNKPELQR GLEARHIELI ALGGTIGVGL FMGAASTLKW AGPSVLLAYI IAGLFVFFIM 
61:	RSMGEMLFLE PVTGSFAVYA HRYMSPFFGY LTAWSYWFMW MAVGISEITA IGVYVQFWFP 
121:	EMAQWIPALI AVALVALANL AAVRLYGEIE FWFAMIKVTT IIVMIVIGLG VIFFGFGNGG 
181:	QSIGFSNLTE HGGFFAGGWK GFLTALCIVV ASYQGVELIG ITAGEAKNPQ VTLRSAVGKV 
241:	LWRILIFYVG AIFVIVTIFP WNEIGSNGSP FVLTFAKIGI TAAAGIINFV VLTAALSGCN 
301:	SGMYSCGRML YALAKNRQLP AAMAKVSRHG VPVAGVAVSI AILLIGSCLN YIIPNPQRVF 
361:	VYVYSASVLP GMVPWFVILI SQLRFRRAHK AAIASHPFRS ILFPWANYVT MAFLICVLIG 
421:	MYFNEDTRMS LFVGIIFMLA VTAIYKVFGL NRHGKAHKLE E