2.A.3.1.17
D-serine/L-alanine/D-alanine/glycine/D-cycloserine uptake porter of 556 aas, CycA. Can be mutated to D-cycloserine (a seconary line antitubercular drug) resistance (Chen et al. 2012).
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| Accession Number: | M1IW84 |
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| Protein Name: | D-serine/alanine/glycine transporter protein cycA |
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| Length: | 556 |
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| Molecular Weight: | 60034.00 |
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| Species: | Mycobacterium bovis BCG str. Korea 1168P [1206780] |
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| Number of TMSs: | 12 |
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| Substrate |
D-alanine, D-serine, L-alanine, D-cycloserine |
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1: MPDDIAAADP TDTQPHLRRD LANRHIQLIA IGGAIGTGLF MGSGRTISLA GPAVMVVYGI
61: IGFFVFFVLR AMGELLLSNL NYKSFVDFAA DLLGPAAGFF VGWSYWFAWV VTGIADLVAI
121: TSYARFWWPG LPIWVPALVT VALILAVNLF SVRHFGELEF WFALIKVAAI VCLIAVGAIL
181: VATNFVSPHG VHATIENLWN DNGFFPTGFL GVVSGFQIAF FAYIGVELVG TAAAETADPR
241: RTLPRAINAV PLRVAVFYIG ALLAILAVVP WRQFASGESP FVTMFSLAGL AAAASVVNFV
301: VVTAAASSAN SGFFSTGRML FGLADEGHAP AAFHQLNRGG VPAPALLLTA PLLLTSIPLL
361: YAGRSVIGAF TLVTTVSSLL FMFVWAMIII SYLVYRRRHP QRHTDSVYKM PGGVVMCWAV
421: LVFFAFVIWT LTTETETATA LAWFPLWFVL LAVGWLVTQR RQSRRSFGFH CQVVGVRQQL
481: GRGMARLAMK IHARPKLRSA VVVEPVSAGE PGARRSAKSV RKLASDDSQS AHCPVAVVGL
541: ADGGRDPQYH HDGPDR