TCDB » SEARCH

« See all members of the family

2.A.3.1.4 γ-aminobutyrate:H⁺ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005).
Accession Number:	P25527
Protein Name:	GabP aka B2663
Length:	466
Molecular Weight:	51080.00
Species:	Escherichia coli [83333]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	hydron, gamma-aminobutyric acid

DIP:	DIP-9724N
RefSeq:	AP_003236.1 NP_417149.1
Entrez Gene ID:	948049
Pfam:	PF00324
BioCyc:	EcoCyc:GABP-MONOMER ECOL168927:B2663-MONOMER
KEGG:	ecj:JW2638 eco:b2663
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015185 F:L-gamma-aminobutyric acid transmembrane tra... GO:0015812 P:gamma-aminobutyric acid transport GO:0055085 P:transmembrane transport
References (5) [1] “Molecular organization of the Escherichia coli gab cluster: nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene.” Niegemann E.et.al. 8297211 [2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MGQSSQPHEL GGGLKSRHVT MLSIAGVIGA SLFVGSSVAI AEAGPAVLLA YLFAGLLVVM 
61:	IMRMLAEMAV ATPDTGSFST YADKAIGRWA GYTIGWLYWW FWVLVIPLEA NIAAMILHSW 
121:	VPGIPIWLFS LVITLALTGS NLLSVKNYGE FEFWLALCKV IAILAFIFLG AVAISGFYPY 
181:	AEVSGISRLW DSGGFMPNGF GAVLSAMLIT MFSFMGAEIV TIAAAESDTP EKHIVRATNS 
241:	VIWRISIFYL CSIFVVVALI PWNMPGLKAV GSYRSVLELL NIPHAKLIMD CVILLSVTSC 
301:	LNSALYTASR MLYSLSRRGD APAVMGKINR SKTPYVAVLL STGAAFLTVV VNYYAPAKVF 
361:	KFLIDSSGAI ALLVYLVIAV SQLRMRKILR AEGSEIRLRM WLYPWLTWLV IGFITFVLVV 
421:	MLFRPAQQLE VISTGLLAIG IICTVPIMAR WKKLVLWQKT PVHNTR

2.A.3.1.4
γ-aminobutyrate:H⁺ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.3.1.4γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.3.1.4
γ-aminobutyrate:H⁺ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005).