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Accession Number: | P25376 |
Protein Name: | Agp1 aka YCL025C aka YCL25C |
Length: | 633 |
Molecular Weight: | 69671.00 |
Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
Substrate | asparagine, glutamine |
Cross database links:
DIP: | DIP-4973N |
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RefSeq: | NP_009905.3 |
Entrez Gene ID: | 850333 |
Pfam: | PF00324 |
KEGG: | sce:YCL025C |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015193
F:L-proline transmembrane transporter activity
GO:0005515
F:protein binding
GO:0006865
P:amino acid transport
GO:0055085
P:transmembrane transport
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References (13)[1] “The complete DNA sequence of yeast chromosome III.” Oliver S.G.et.al. 1574125 [2] “The Saccharomyces cerevisiae YCC5 (YCL025c) gene encodes an amino acid permease, Agp1, which transports asparagine and glutamine.” Schreve J.L.et.al. 9573211 [3] “Cysteine uptake by Saccharomyces cerevisiae is accomplished by multiple permeases.” During-Olsen L.et.al. 10467005 [4] “Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae.” Regenberg B.et.al. 10654085 [5] “Amino acid signaling in Saccharomyces cerevisiae: a permease-like sensor of external amino acids and F-Box protein Grr1p are required for transcriptional induction of the AGP1 gene, which encodes a broad-specificity amino acid permease.” Iraqui I.et.al. 9891035 [6] “Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids.” Forsberg H.et.al. 11154269 [7] “Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii.” Brachat S.et.al. 12844361 [8] “Global analysis of protein expression in yeast.” Ghaemmaghami S.et.al. 14562106 [9] “Yeast Agp2p and Agp3p function as amino acid permeases in poor nutrient conditions.” Schreve J.L.et.al. 14697254 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MSSSKSLYEL KDLKNSSTEI HATGQDNEIE YFETGSNDRP SSQPHLGYEQ HNTSAVRRFF 61: DSFKRADQGP QDEVEATQMN DLTSAISPSS RQAQELEKNE SSDNIGANTG HKSDSLKKTI 121: QPRHVLMIAL GTGIGTGLLV GNGTALVHAG PAGLLIGYAI MGSILYCIIQ ACGEMALVYS 181: NLTGGYNAYP SFLVDDGFGF AVAWVYCLQW LCVCPLELVT ASMTIKYWTT SVNPDVFVII 241: FYVLVITINI FGARGYAEAE FFFNCCKILM MTGFFILGII IDVGGAGNDG FIGGKYWHDP 301: GAFNGKHAID RFKGVAATLV TAAFAFGGSE FIAITTAEQS NPRKAIPGAA KQMIYRILFL 361: FLATIILLGF LVPYNSDQLL GSTGGGTKAS PYVIAVASHG VRVVPHFINA VILLSVLSMA 421: NSSFYSSARL FLTLSEQGYA PKVFSYIDRA GRPLIAMGVS ALFAVIAFCA ASPKEEQVFT 481: WLLAISGLSQ LFTWTAICLS HLRFRRAMKV QGRSLGELGF KSQTGVWGSA YACIMMILIL 541: IAQFWVAIAP IGEGKLDAQA FFENYLAMPI LIALYVGYKV WHKDWKLFIR ADKIDLDSHR 601: QIFDEELIKQ EDEEYRERLR NGPYWKRVVA FWC