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2.A.3.3.3
Amino acid transporter, AAT1 or CAT1, of 594 aas and 14 TMSs. It is a high-affinity permease involved in the transport of the cationic amino acids (e.g., arginine, lysine, histidine, citrulline, valine, and glutamate). It transports mostly basic amino acids, and, to a lesser extent, neutral and acidic amino acids. It probably functions as a proton symporter. It transports histidine with a Km of 35 μM at Ph 4.5, the optimal pH for this system (Frommer et al. 1995).  Amino acid transporter (AAT) genes regulate seed protein content in chickpea (Cicer arietinum L.) (Kalwan et al. 2023).

Accession Number:Q84MA5
Protein Name:Cationic amino acid transporter 1
Length:594
Molecular Weight:64847.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate L-glutamate(1-), alpha-amino acid, L-lysine, L-citrulline, L-arginine, L-valine, L-histidine

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FASTA formatted sequence
1:	MASGGGDDGL RRRGCSCTKD DFLPEESFQS MGNYLKALKE TPSRFMDRIM TRSLDSDEIN 
61:	EMKARSGHEM KKTLTWWDLM WFGIGAVIGS GIFVLTGLEA RNHSGPAVVL SYVVSGVSAM 
121:	LSVFCYTEFA VEIPVAGGSF AYLRVELGDF MAFIAAGNII LEYVVGGAAV ARSWTSYFAT 
181:	LLNHKPEDFR IIVHKLGEDY SHLDPIAVGV CAIICVLAVV GTKGSSRFNY IASIIHMVVI 
241:	LFVIIAGFTK ADVKNYSDFT PYGVRGVFKS AAVLFFAYIG FDAVSTMAEE TKNPGRDIPI 
301:	GLVGSMVVTT VCYCLMAVTL CLMQPYQQID PDAPFSVAFS AVGWDWAKYI VAFGALKGMT 
361:	TVLLVGAIGQ ARYMTHIARA HMMPPWLAQV NAKTGTPINA TVVMLAATAL IAFFTKLKIL 
421:	ADLLSVSTLF IFMFVAVALL VRRYYVTGET STRDRNKFLV FLGLILASST ATAVYWALEE 
481:	EGWIGYCITV PIWFLSTVAM KFLVPQARAP KIWGVPLVPW LPSASIAINI FLLGSIDTKS 
541:	FVRFAIWTGI LLIYYVLFGL HATYDTAKAT LKEKQALQKA EEGGVVADNS CSAT